摘要
目的:探讨老年心肌梗死患者冠脉介入干预前后血清心肌肌钙蛋白I(cardiac troponin I,c Tn I)、白细胞介素6(interleukin-6,IL-6)及P选择素(P-selectin,Ps)水平变化的临床意义。方法:选取心肌梗死患者64例作为冠脉介入治疗组,同期体检健康老年人62例作为对照组,采用酶联免疫法检测介入治疗前后c Tn I、IL-6和P选择素水平。结果:老年心肌梗死患者介入治疗前Tn I和Ps水平显著高于对照组,IL-6水平明显低于对照组(P<0.05);冠脉介入手术治疗前后,老年心肌梗死患者的上述指标发生变化,其差异具有统计学意义(P<0.05);冠脉介入治疗后的指标与对照组相比无差异(P>0.05)。结论:老年心肌梗死患者冠脉介入治疗可以降低机体的c Tn I和Ps水平,升高IL-6水平,改善患者心功能,具有一定的临床意义。
Objective To investigate clinical significance of changes of serum cardiac troponin I （cTnI）, interleukin-6 （IL-6） and P-selectin levels in elderly patients with myocardial infarction before and after PCI （percutaneous coronary intervention）.Methods： 64 patients with myocardial infarction were selected as the treatment group, and 62 healthy aged people for health examination at the same time were used as control group. The levels of cTnI, IL-6 and P before and after PCI were detected by enzyme-linkedimmunosorbent assay. Results： Before PCI, the cTnI and Ps levels of treatment group were significantly higher than that of controlgroup, while the IL-6 level was significantly lower than that of control group （P〈0. 05）. The changes of the above parameters in theelderly patients with myocardial infarction before and after PCI were significantly different （P〈0. 05）, while the differences betweentreatment group and control group were not significant （P〈0. 05）. Conclusions： For the elderly patients with myocardial infarction,the coronary intervention can reduce the cTnI and Ps levels, increase the IL-6 level and improve heart function, and has a certain clinical significance.
出处
《中国民康医学》
2016年第6期76-77,87,共3页
Medical Journal of Chinese People’s Health
