摘要
目的探讨诊断梅毒螺旋体感染中ELISA法的检验分析效果。方法收集我院2014年8月至2015年8月入院的70例接受疑似梅毒螺旋体感染治疗的患者，分别对所有患者采用梅毒螺旋体ELISA试验（ELISA法）及快速血浆反应素试验（RPR法）进行检测，比较两种方法的检测结果以及诊断效能等。结果临床确诊梅毒患者50例，非患者20例；患者RPR法检测阳性43例（61．4％），检测阴性27例（38．6％）；患者ELISA法检测阳性47例（67．1％），检测阴性23例（32．9％）；ELISA法灵敏度90．0％，漏诊率10．0％，特异度93．3％，误诊率6．7％，正确指数83．3％；RPR法灵敏度80．0％，漏诊率20．0％，特异度85．0％，误诊率15．0％，正确指数65．0％；ELISA法的灵敏度、特异度及正确指数均高于RPR法；ELISA法的漏诊率及误诊率均低于RPR法。结论诊断梅毒螺旋体感染中ELISA法的检验分析效果显著，具有临床诊断借鉴意义。
Objective To investigate the effect of ELISA method in the diagnosis of treponema pallidum infection. Methods 70 patients with suspected treponema pallidum infection treated in our hospital from August 2014 to August 2015 were collected, all patients underwent treponema pallidum ELISA assay （ELISA method） and rapid plasma reagin （RPR method） testing. Test results and diagnostic performance of two methods were compared. Results There were 50 patients with clinical diagnosis of syphilis, 20 cases of non-patient. There were 43 positive cases （61.4%） detected by RPR, 27 negative cases （38.6%）; there were 47 positive cases （67.1%） detected by ELISA, 23 negative cases （32.9%）. The sensitivity of ELISA method was 90.0%, missed diagnosis rate was 10.0%, specificity was 93.3%, misdiagnosis rate was 6.7%, correct index was 83.3%; the sensitivity of RPR method was 80.0%, missed diagnosis rate was 20.0%, specificity was 85.0%, misdiagnosis rate was 15.0%, correct index was 65.0%; sensitivity, specificity and correct index of ELISA method were higher than those of RPR method, missed diagnosis rate and misdiagnosis rate of ELISA method were lower than those of RPR method. Conclusion ELISA method in the diagnosis of treponema pallidum infection has significant diagnostic performance, worthy of clinical promotion.
出处
《国际医药卫生导报》
2016年第7期996-998,共3页
International Medicine and Health Guidance News
