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链霉蛋白酶在胃镜检查中的应用价值 被引量:13

Application value of pronase in gastroscopy
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摘要 目的探讨链霉蛋白酶在胃镜检查中的应用价值。方法将204例接受胃镜检查的患者分为实验组和对照组。对照组在胃镜检查前服用盐酸利多卡因胶浆,实验组服用盐酸利多卡因胶浆及链霉蛋白酶。观察两组胃内视野清晰度及不良反应。比较实验组中不同链霉蛋白酶服药时间患者的胃内视野清晰度。结果实验组胃内视野清晰度的有效率73.96%(71/96),高于对照组的41.67%(45/108),差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。实验组按胃镜检查前服用链霉蛋白酶的时间分为服药时间<20 min的患者48例,服药时间≥20 min的患者48例,其胃镜检查视野清晰度的有效率比较,差异无统计学意义(P>0.05)。结论胃镜检查前联合应用链霉蛋白酶及盐酸利多卡因胶浆,可明显提高胃内视野的清晰度,且无明显不良反应,安全性较高。 Objective To explore the application value of pronase in gastroscopy. Methods A total of 204 patients accepting gastroscopy were divided into experimental group and control group. Before gastroseopy ,the control group was orally administered lidocaine hydroehloride mucilage, and the experimental group was orally administered lidocaine hydrochloride mucilage and pronasc. The clarity of vision in the stomach and adverse reactions were observed in both groups. And in the experimental group, the clarity of vision in the stomach was compared between the patients with different times of taking pronase. Results The effective rate of clarity of vision in the stomach in the experimental group was 73.96% (71/96), and higher than that in the control group (41.67% ,45/108 ) (P 〈 0.05 ). There was no significant difference in the incidence of adverse reactions between two groups ( P 〉 0.05 ). The time of taking pronase was less than 20 minutes in 48 cases,20 and more than 20 minutes in 48 cases,and there was no significant difference in the effective rate of gastroscopy for determining clarity of vision in the stomach between two groups ( P 〉 0.05 ). Conclusion Application of pronase combined with lidocaine hydrochloride mucilage before gastroseopy can significantly improve the clarity of vision in the stomach, and is safe without obvious adverse reactions.
出处 《广西医学》 CAS 2016年第2期221-222,229,共3页 Guangxi Medical Journal
关键词 胃镜检查 链霉蛋白酶 胃内清晰度 Gastroscopy,Pronase, Clarity of vision in the stomach
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