期刊文献+

心脏型脂肪酸结合蛋白和缺血修饰蛋白在急性心肌梗死诊断中的应用 被引量:2

暂未订购
导出
摘要 目的探讨心脏型脂肪酸结合蛋白(H-FABP)和缺血修饰蛋白(IMA)在急性心肌梗死(AMI)早期诊断中的应用价值。方法选择2012年1月至2014年12月在本院心内科就诊的胸痛患者79例,包括AMI胸痛患者49例,非AMI胸痛患者30例,患者在入院时0h、3h、6h、9h、12h分别抽取静脉血。采用免疫层析法检测H-FABP,白蛋白-钴离子结合试验检测IMA。结果AMI患者在胸痛发作3-6h H-FABP和IMA阳性率高,9—12h肌酸激酶同工酶(CK-MB)和肌钙蛋白I(cTnI)阳性率高。6h时H-FABP、IMA的敏感度和阴性预测值显著高于CK-MB、cTnI。结论新的心肌损伤标志物H-FABP和IMA在发病6h以内的早期胸痛患者中,诊断AMI的敏感性较高,具有较高的临床应用价值。
出处 《浙江临床医学》 2016年第4期751-752,共2页 Zhejiang Clinical Medical Journal
  • 相关文献

参考文献5

二级参考文献14

  • 1Nakata T, Hashimoto A, Hase M, et al. Human heart-type fatty acid-binding protein as an early diagnostic and prognostic marker in acute coronary syndrome [J]. Cardiology, 2003, 99 (2): 96-104.
  • 2Cavus U, Coskun F, Yavuz B, et al. Heart-type, fatty-acid binding protein can be a diagnostic marker in acute coronary syndromes [J]. J Natl Med Assoc, 2006, 98 (7) : 1067-1070.
  • 3Thygesen K, Alpert JS, White HD, et al. Universal definition of myocardial infarction [J]. J Am Coll Cardiol, 2007, 50 (22) : 2173-2195.
  • 4Braunwald E, Antman EM, Beasley JW, et al. ACC/AHA guideline update for the management of patients with unstable angina and non-ST-segment elevation myoem-dial infarction-2002: summary article: a report of the American College of Cardiology/ American Heart Association Task Force on Practice Guidelines ( Committee on the Management of Patients With Unstable Angina) [J]. Circulation, 2002, 106 (14): 1893-1900.
  • 5Salerno SM, Alguire PC, Waxman HS. Competency in interpretation of 12-lead electrocardiograms : a summary and appraisal of published evidence [J]. Ann Intern Med, 2003, 138 (9) : 751- 760.
  • 6Newby LK, Goldmann BU, Ohman EM. Troponin: an important prognostic marker and risk-stratification tool in non-ST-segment elevation acute coronary syndromes [ J]. J Am Coil Cardiol, 2003, 41 (4 Supple S) : $31-36.
  • 7Roger VL, Killian JM, Weston SA, et al. Redefinition of myocardial infarction: prospective evaluation in the community [J]. Circulation, 2006, 114 (8) : 790-797.
  • 8O' Donoghue M, de Lemos JA, Morrow DA, et al. Prognostic utility of heart-type fatty acid binding protein in patients with acute coronary syndromes [ J ]. Circulation, 2006, 114 (6) : 550- 557.
  • 9McMahon CG, Lamont JV, Curtin E, et al. Diagnostic accuracy of heart-type fatty acid-binding protein for the early diagnosis of acute myocardial infarction [J]. Am J Emerg Med, 2012, 30 ( 2 ) : 267-274.
  • 10Kim KS, Lee H J, Kim K, et al. Heart-type fatty acid binding protein as an adjunct to cardiac troponin-I for the diagnosis of myocardial infarction [J]. J Korean Med Sci, 2011, 26 (1): 47 -52.

共引文献18

同被引文献23

引证文献2

二级引证文献11

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部