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In this issue(December 2015)

In this issue(December 2015)
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摘要 This issue starts with a meta-analysis by Liu and colleagues^([1])about the effectiveness of adjunctive treatment with metformin to reduce the weight gain associated with clozapine use in patients with schizophrenia.The relatively common occurrence of the metabolic syndrome among individuals taking clozapine^([2])is a major problem for the minority This issue starts with a meta-analysis by Liu and colleagues about the effectiveness of adjunctive treatment with metformin to reduce the weight gain associated with clozapine use in patients with schizophrenia.The relatively common occurrence of the metabolic syndrome among individuals taking clozapine is a major problem for the minority of difficult-to-treat patients for whom clozapine is the only effective agent for treating their psychosis.
出处 《上海精神医学》 CSCD 2015年第6期328-330,共3页 Shanghai Archives of Psychiatry
关键词 出版社 中国 读者
分类号 R749 [医药卫生—神经病学与精神病学]
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  • 1Jiskeliinen E, Haapea M, Rautio N, Juola P, Penttil M, Nordstr6met T, et al. Twenty years of schizophrenia research in the Northern Finland birth cohort 1966: a systematic review. Schizophr Res Treatment. 2015; 2015: 524-875. doi: http://dx.doi.org/10.1155/2015/524875.
  • 2Hasnain M, Vieweg WV, Fredrickson SK. Metformin for atypical antipsychotic-induced weight gain and glucose metabolism dysregulation: review of the literature and clinical suggestions. CNS Drugs. 2010; 24(3): 193-206. doi: http://dx.doi.org/10.2165/115301.
  • 3Alvarez-Jimenez M, Gonzalez-Blanch CFB, Hetrick S, Rodriguez-Sanchez J, Perez-lglesias R, Vazquez-Barquero J. Antipsychotic-induced weight gain in chronic and first- episode psychotic disorders: a systematic critical reappraisal. CNS Drugs. 2008; 22(7): 547-562.
  • 4Wu RR, Jin H, Gao KM, Twamley EW, Ou J J, Shao F, et al. Metformin for treatment of antipsychotic-induced amenorrhea and weight gain in women with first-episode schizophrenia: a double-blind, randomized, placebo- controlled study. Am J Psychiatry. 2012; 169(8): 813-821. doi: http://dx.doi.org/lO.1176/appi,ajp.2012.11091432.
  • 5Wu RR, Zhao JP, Guo XF, He YO,, Fang MS, Guo WB, et al. Metformin addition attenuates olanzapine-induced weight gain in drug-naive first-episode schizophrenia patients: a double-blind, placebo-controlled study. Am J Psychiatry. 2008; 165(3): 352-358. doi: http://dx.doi.org/20.1276/appi. ajp.2007.07020079.
  • 6Wu RR, Zhao JP, Jin H, Shao P, Fang MS, Guo XF, et al. Lifestyle intervention and metformin for treatment of ant-ipsychotic- induced weight gain: a randomized controlled trial. JAMA. 2008; 299(2): 185-193. doi: http://dx.doi.org/lO.lO01/ jama.2007.56-b.
  • 7Carrizo E, Fernandez VL, Connell L, Sandia I, Prieto D, Mogoll6n J, et al. Extended release metformin for metabolic control assistance during prolonged clozapine administration: a 14 week, double-blind, parallel group, placebo-controlled study. Schizophrenia Res. 2009; 113(1): 19-26. doi: http://dx.doi.org/10.1016/j.schres.2009.05.007.
  • 8Wu RR, Zhang F, Gao KM, Ou J J, Shao P, Jin H, et al Metformin treatment of antipsychotic-induced dyslipidemia an analysis of two randomized, placebo-controlled trials Mol Psychiaty. 2026; Epub 26 Jan 2026. doi: http://dx.doi org/lO.2038/mp.2015.221.
  • 9Schaefer M, Leopold K, Hinzpeter A, Heinz A, Krebs M. Memant-ine-associated reversal of clozapine-induced weight gain. Pharmacopsychiatry. 2007; 40(4): 149-151. doi: http:// dx.doi.org/10.1055/s-2007-984391.
  • 10Reis de Sa A Jr, Elkis H. Comments on "Weight gain management in patients with schizophrenia during treatment with olanzapine in association with nizatidine". Rev Bras Psiquiatr. 2007; 29(1): 90. doi: http://dx.doi. or/10.1590/$1516-44462007000200025.

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上海精神医学
2015年 第6期

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