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Wnt/β-Catenin信号通路对肿瘤干细胞作用的研究进展 被引量:13

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摘要 肿瘤干细胞(CSC)存在于多种实体瘤中,是导致肿瘤复发及耐药的主要原因。Wnt/β-catenin信号通路在乳腺癌、肺癌、前列腺癌等CSC的自我更新、成瘤及分化中发挥重要作用。Wnt/β-catenin信号通路各调节点是未来复发性及难治性肿瘤治疗的潜在靶点。
作者 李月雅 李凯
出处 《山东医药》 CAS 北大核心 2016年第9期98-100,共3页 Shandong Medical Journal
基金 天津市应用基础及前沿技术研究计划项目(11JCYBC11300)
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