摘要
利用海南霉素钠、甲氧苄啶、乳化剂和适宜溶媒制备了复方海南霉素钠溶液,并对其质量进行了评价,在此基础上进一步观察了制备的复方海南霉素钠溶液对人工感染鸡球虫病的治疗效果。结果表明,制备的复方海南霉素钠溶液显深蓝色,含海南霉素钠为标示量的98.86%,稳定性试验重点考察项目均符合标准要求;人工感染球虫的试验组鸡群服用复方海南霉素钠溶液后,发生下痢的鸡只数和死亡鸡只数最少,且有效治愈率最高,为95%,明显高于2个对照组。制备的复方海南霉素钠溶液质量稳定,对鸡球虫感染具有良好的治疗效果。
The compound hainanmycin sodium solution was prepared by using hainanmycin sodium, trimethoprim, emulsifier and proper solvent. The quality of the prepared solution was evaluated using the method recommended by national standard. Furthermore, the therapeutic efficacy of compound hainanmyein sodium solution on artificial infection of coccidian in chicken was investigated. The color of the prepared hainanmycin sodium solution was dark blue, and the content of hainanmycin sodium in the solution was 98.86% of the labeled amount. All of the crucial indexes investigated in stability test met standard requirements. The number of chickens with diarrhea and death chickens in the group administrated with compound hainanmycin sodium solution was fewest, and the effective cure rate was the highest （95%）, which was obviously higher than that of the two control groups. The quality of the prepared compound hainanmycin sodium solution was stable, and it showed obvious therapeutic efficacy on chicken coccidiosis.
出处
《畜牧与饲料科学》
2016年第1期40-41,45,共3页
Animal Husbandry and Feed Science
基金
山东德州神牛药业有限公司发明专利项目专项基金(专利号:201310574864)
关键词
海南霉素钠
甲氧苄啶
乳化剂
疗效试验
hainanmycin sodium
trimethoprim
emulsifier
curative effect
