摘要
患者女,56岁。全身褐色扁平疣状丘疹40年,面颈部多发疣状增生物8年。腹壁、左前臂及手背皮疹组织病理示:角化过度,棘层增厚,表皮上部可见弥漫性细胞空泡化,细胞大小不一,胞质呈钢灰色。额面部皮疹组织病理示:表皮角化过度伴角化不全,棘层肥厚,肿瘤细胞位于表皮内,全层细胞排列紊乱,部分不典型;毛囊和汗腺导管细胞核大深染,可见异型改变。诊断为疣状表皮发育不良伴多发Bowen病。
A 56-year-old woman presented with brown flat verrucous papules all over the body for 40 years and multiple verrucous plaques for 8 years. Lesions histopathology on the abdominal skin,left forearm and opisthenar showed hyperkeratosis,acanthosis,diffuse cell vacuolation and irregularly sized cells on epidermis,of which cytoplasm were steel-gray. Lesions on the forehead and face revealed epidermis hyperkeratosis accompanied with parakeratosis and acanthosis,and the tumor cells were located in epidermis,with cells of the whole level in disorder and partial atypical. Deep-dyed big nudeolus and abnormal model change were observed on cells of the hair follicles and sweat glands catheter. Epidermodysplasia verruciformis combined with multiple Bowen disease was diagnosed.
出处
《中国皮肤性病学杂志》
CAS
CSCD
北大核心
2016年第3期286-288,共3页
The Chinese Journal of Dermatovenereology
