摘要
目的探讨经鼻与经口气管插管在急性颅脑病变所致呼吸衰竭患者的临床疗效的对比研究。方法将急性颅脑病变需机械通气患者,随机分为经口气管插管组和经鼻气管插管组,比较2组患者的ICU住院时间、28d病死率、机械通气时间、意外拔管发生率等疗效评估。结果经口气管插管组和经鼻气管插管组的28d病死率及呼吸机相关肺炎发病率比较,差异无统计学意义(P>0.05)。经口气管插管组生存患者平均机械通气时间为(158.1±74.3)h,ICU住院时间为(7.9±3.4)d,意外脱管及再次插管1例;而经鼻气管插管组生存患者平均机械通气时间为(123.9±64.6)h,ICU住院时间为(6.4±2.9)d,两者比较差异有统计学意义(P<0.05)。结论对颅脑疾病所致呼吸衰竭,实施经鼻气管插管机械通气具有明显缩短ICU治疗时间、机械通气时间,减少意外拔管率,同时不增加呼吸机相关性肺炎及病死率,不影响患者预后。
Objective To explore the clinical effect of nasotracheal or mouth intubati in patients with respiratory failure caused by acute brain disease.Methods Patients with respiratory failure caused by acute brain disease were divided randomly into nasotracheal intubati group and mouth intubati group.The clinical features such as hospital stays in ICU,mortality rate of 28 days,mechanical ventilation time,and incidence rate of unexpected extubate were observed and compared in the two groups.Results There were no significantly of the rate of 28 days mortality and ventilator associated pneumonia between the two groups.Compared to mouth intubati group,mean mechanical ventilation time(158.1±74.3hvs.123.9±64.6h),hospital stays in ICU(7.9±3.4dvs.6.4±2.9d),and the incidence rate of unexpected extubate(1case vs.0case)were decreased in nasotracheal intubati group(P〈0.05).ConclusionNasotracheal intubati decreased mechanical ventilation time,hospital stays in ICU and the incidence rate of unexpected extubate.It is efficient and safe,and worthy of being recommended for use in clinical practice.
出处
《检验医学与临床》
CAS
2016年第4期472-474,共3页
Laboratory Medicine and Clinic
关键词
经鼻气管插管
经口气管插管
颅脑疾病
机械通气
nasotracheal intubati
mouth intubati
brain disease
mechanical ventilation