摘要
目的探讨西安地区儿童急性中耳炎分泌物细菌培养及药物敏感试验。方法选取2014年1~6月该院就诊的290例急性中耳炎患儿分泌物常规细菌培养及常用药物敏感性试验。结果 290例患儿共分离出病原菌267株,包括革兰阳性球菌150株,占56.18%,其主要由金黄色葡萄球菌、肺炎链球菌及凝固酶阴性葡萄球菌等构成;革兰阴性杆菌94株,占35.21%,其主要由铜绿假单胞菌、肺炎克雷伯菌、流感嗜血杆菌、奇异变形杆菌、大肠埃希菌等构成;真菌占6.74%,主要为念珠菌属。结论该地区儿童急性中耳炎的常见致病菌为金黄色葡萄球菌、肺炎链球菌、凝固酶阴性葡萄球菌、铜绿假单胞菌。不同种类病原菌对抗菌药物的敏感性及耐药性不同,可用于指导临床合理有效使用抗菌药物,提高临床治愈率。
Objective To investigate the bacterial culture and drug sensitivity test of secretion in children with acute otitis media（AOM）in Xi′an area.Methods Ear discharge of 290 children with AOM in our hospital between January and June of 2014 were collected for pathogen isolation and drug sensitivity test.Results A total of 267 strains of pathogens were isolated,including 150strains（56.18%）of gram-positive cocci,mainly consisting of Staphylococcus aureus,Streptococcus pneumonia and coagulase-negative Staphylococcus,and 94strains（35.21%）of gramnegative cocci,including Pseudomonas aeruginosa,Klebsiella pneumonia,Haemophilus influenza,Proteus mirabilis,and Escherichia coli.Fungi strains were mainly Candida（6.74%）.Conclusion The most common pathogen of AOM in children in Xi′an were Staphylococcus aureus,Streptococcus pneumonia,coagulase-negative Staphylococcus and Pseudomonas aeruginosa.Different pathogens exhibit distinct sensitivity and drug resistance against antibiotics.Therefore,results of this study provided a guideline for the rational drug use for treating children with AOM and avoided drug resistance.Morever it could improve recovery rate of the children.
出处
《检验医学与临床》
CAS
2016年第4期457-459,共3页
Laboratory Medicine and Clinic
基金
陕西省科学技术研究发展计划项目(2013K12-12-04)
关键词
急性中耳炎
细菌培养
药敏试验
抗菌药物
AOM
Bacterial culture
drug sensitivity test
antibiotic drug resistance
