摘要
目的:通过小儿危重病例评分评估重症手足口病患儿入院时病情严重程度,并分析该评分系统对预后(并发症和结局)的预测能力。方法:选取2010年1月至2014年6月入住我院重症监护室,符合重症手足口病诊断标准的患儿123例。收集PCIS评分系统的相关生理参数及结局资料,通过受试者工作特征曲线(ROC)下的面积来评估评分系统对并发症、结局和后遗症的预测能力。结果:通过PCIS评价重症手足口病患儿病情,存活组患儿评分的中位数明显高于死亡组患儿(Z=-8.82,P=0.00)。病情评估发现危重型病例仅有10例(8.13%)。小儿危重病例分辨是否发生并发症、死亡和后遗症的AUROC和95%可信区间分别为0.78(0.70,0.88)、0.86(0.78,0.95)和0.84(0.77,0.89)。结论:小儿危重病例评分不能充分评价重症手足口病病情的严重程度,需要探索更能反映手足口病病情严重程度的指标。
Objective： To evaluate the severity degree of severe hand,foot and mouth disease（ HFMD） by pediatric critically illness score（ PCIS）,analyze its predictive ability in progression. Methods： One hundred and twenty three severe HFMD children were recruited in the study from Jan 2010 to June 2014.Physiological parameters correlatively and outcome data of PCIS were collected. The area under the receiver operating characteristic（ AUROC） were used to assess the complication,outcome and sequela in severe HFMD.Results： The median of PCIS for death children was lower than survived children（ Z =-8.82,P = 0.00）. The AUROC（ 95% confidence interval） were 0.78（ 0.70,0.88）,0.86（ 0.78,0.95）,0.84（ 0.77,0.89） for PCIS to distinguish whether the complication,death and sequela occour. Conclusion： PCIS cannot adequately evaluate the severity of HFMD. Therefore,the other physiological parameters are included in order to more objectively evaluate the severity of HFMD.
出处
《儿科药学杂志》
CAS
2016年第2期8-10,共3页
Journal of Pediatric Pharmacy
关键词
小儿危重病例评分
病情严重程度
重症
手足口病
pediatric clinical illness score
severity degree of disease
severe
hand
foot and mouth disease
