摘要
目的:探讨针药结合治疗寒湿证腰椎间盘突出症的临床疗效及其可能作用机制。方法:将70例患者按随机数字表法分为针药组和中药组两组,每组35例。针药组予针刺和肾着汤加减方治疗,中药组予肾着汤加减方治疗。两组均以7天为1个疗程,治疗2个疗程。观察治疗前后的VAS评分及血清IL-6、TNF-α,并评价临床疗效。结果:针药组的总有效率91.43%,高于对照组的74.29%(P<0.05);治疗后两组VAS评分及血清IL-6、TNF-α较本组治疗前均下降(P<0.05),组间比较针药组的改善优于中药组(P<0.05)。结论:针药结合治疗寒湿证腰椎间盘突出症具有较好的临床疗效,并能减轻患者疼痛,其作用机制可能与降低患者血清IL-6、TNF-α水平进而抑制炎症反应有关。
Objective： To observe the therapeutic effect on lumbar disc herniation of cold-dampness syndrome treated by acupuncture combined with Shenzhuo decoction and its mechanism.Methods： Seventy cases were randomly divided into an observation group and a control group,with thirty-five cases in each group.The observation group was treated by acupuncture combined with Shenzhuo decoction,and the control group was treated by Shenzhuo decoction.Seven days was taken as a course of treatment,and the observation included two courses.Their VAS score,serum IL-6,serum TNF-α and the therapeutic effect were observed and analyzed comparatively.Results： The total effective rate of observation group was 91.43%,and there was statistical differences compared with control group（ P〈0.05）,and their VAS score,serum IL-6 and serum TNF-α were decreased after treatment（ P〈0.05）.The observation group improved better than the control group,and there was a statistical difference between them（ P〈0.05）.Conclusion： Acupuncture combined with Shenzhuo decoction has an obviously therapeutic effect for the treatment of lumbar disc herniation of cold-dampness syndrome,and its mechanism might be related to the descent of serum IL-6 and serum TNF-α.
出处
《针灸临床杂志》
2016年第1期8-10,共3页
Journal of Clinical Acupuncture and Moxibustion
