摘要
目的：探讨温州地区儿童支气管扩张症的病因、影像和病原学特点。方法：对1997年1月-2013年3月温州医科大学附属育英儿童医院呼吸科收治的55例支气管扩张症惠儿的临床资料进行回顾性分析。结果：呼吸道感染导致的支气管扩张症34例（占61．82％），其他病因包括：支气管异物2例（占3．64％），先天性免疫缺陷病2ff0（占3．64％），原发性纤毛功能障碍2例（占3．64％），先天性呼吸系统发育畸形3例（占5．45％），支气管哮喘4例（占7．27％），变应性支气管肺曲霉菌病（ABPA）1例（占1．82％），炎症性肠病（IBD）1例（占1．82％），未明确病因6例（占10．91％）。胸部x线片有阳性提示的8例（占14．55％），胸部高分辨率CT（HRCT）检查阳性率达lOO．00％，差异有统计学意义（x2=82．0，P〈0．05）。共送检100份呼吸道标本，检出病原菌35株，以铜绿假单胞菌（PA）最为常见。结论：呼吸道感染是温州地区儿童支气管扩张症最常见的病因，HRCT是确诊的主要手段，病原菌分布以革兰阴性菌尤其是PA为主。
Objective： To explore the etiology, imaging characteristics and pathogen distribution of the bronchiectasis children in Wenzhou, Methods： Datas of 55 patients with bronchiectasis from January 1997 to March 2013 were retrospectively analyzed. Results： The main cause ofbronchiectasis in 34 cases was respiratory tract infection （61.82%）. Other causes induded 2 cases of bronchial foreign bodies （3.64%）, 2 cases of congenital immunodeficiency disease （3.64%）, 2 cases of primary cilia dysfunction （3.64%）, 3 cases of congenital respira- tory system malformations （5.45%）, 4 cases of bronchial asthma （7.27%）, 1 case of allergic bronchial pulmonary aspergillosis （1.82%）, 1 case of inflammatory bowel disease （1.82%）, and 6 cases of unknown reasons. Eight cas- es （14.55%） had positive hints in Chest X-ray, while chest high-resolution CT （HRCT） was 100%, and the differ- ence was statistically significant （x2=82.0, P〈0.05）. Sputum examination results of 35 （35%） were positive in 100 specimens. Pseudomonas aeruginosa was the most common （31.82%）. Conclusion： Respiratory tract infection is the most common cause of bronchiectasis in the Wenzhou area. HRCT is a major method of diagnosis. Gram- negative bacteria infection is the main pathogen, especially pseudomonas aeruginosa.
出处
《温州医科大学学报》
CAS
2016年第2期140-143,共4页
Journal of Wenzhou Medical University
关键词
支气管扩张症
病因
病原
影像学
儿童
bronchiectasis
etiology
pathogen
radiography
children
