摘要
目的分析2004和2013年北京市6~17岁儿童肥胖类型与心血管代谢异常情况。方法资料来源于2004和2013年对北京市6-17岁儿童开展的两次现况调查。于2004年采用分层整群抽样方法,从北京市西城、东城、朝阳、海淀、大兴、平谷及延庆区的所有学校中抽取20所中小学校,对抽样学校的全部20544名6。17岁儿童进行身高、体重、腰围及血压测量,并对其中1所学校的962名儿童进行静脉血生化指标(FPG、TC、TG、HDL-C、LDL-c)检测。于2013年,采用与2004年相同的抽样方法,从北京市海淀和东城区的4所中小学校(包含2004年参加抽血实验的学校)中抽取7211名6~17岁儿童进行相同指标的测量,并对2004年参加抽血的学校的1344名儿童抽取静脉血进行生化指标的检测。采用独立样本t检验比较2004与2013年儿童BMI、腰围、腰围身高比(WHtR)的差异;采用x。检验比较高血压、空腹血糖受损(IFG)、血脂异常、代谢异常个数在2004和2013年的检出率及在不同肥胖类型中的检出率差异。采用logistic回归模型分析不同类型肥胖与心血管代谢异常的关系。结果2013年北京市男童BMI为(20.3±4.4)kg/m2、腰围为(70.6±12.8)cm、WHtR为0.451士0.064,均高于2004年[(19.4±4.2)kg/m2、(66.7±11.8)cm、0.437±0.059](t值分别为11.18、17.20、11.64,P值均〈0.001);女童BMI为(18.9±3.6)kg/m。、腰围为(64.5±9.6)em、WHtR为(0.430±0.047),均高于2004年[(18.7±3.7)kg/m2、(63.0±9.3)cm、(0.423±0.047)](t值分别为12.21、8.15、14.13,P值均〈0.001)。复合型肥胖罹患率从2004年的8.27%(1697/20526)~升到2013年的10.74%(774/7209),中心型肥胖从3.08%(632/205261上升至4.44%f320/7209)。2013年高血压、IFG、高Tc、高TG检出率分别为10.78%(313/1344)、49.54%(664/1344)、11.53%(155/1344)、7.51%(101/1344),均高于2004年[4.29%(42/962)、6.45%(63/962)、5.03%(49/962)、3.59%(35/962)](x。值分别为36.76、506.61、28.31、29.59,P值均〈0.001)。复合型肥胖组儿童高血压(OR=5.88,95%CI:4.42~7.82)、高TG(OR=7.12,95%:4.35~11.64)、低HDL—C(OR=3.04,95%CI:1.55—5.95)、高LDL—C(OR=2.27,95%CI:1.22±4.02)、代谢异常个数≥2(OR=3.07,95%CI:2.09。4.50)的发生风险均较高。结论2013年北京市6—17岁儿童3种肥胖检出率均高于2004年;除低HDL—C及高LDL-C外,其他心血管代谢危险因素异常检出率均高于2004年;复合型肥胖心血管代谢异常的检出率较高。
Objective To examine the prevalence of obesity phenotypes and cardiometablic disorders (CDs) among children aged 6-17 in Beijing from 2004 to 2013. Methods Data were obtained from two cross-section surveys, which were conducted in 2004 and 2013. In 2004, by using stratified cluster sampling design, 20 primary or middle schools were selected from 7 districts (Xicheng, Dongcheng,Chaoyang, Haidian, Daxing, Pinggu, and Yanqing) in Beijing, and 20 554 school children aged 6-17 were recruited, with weight, height, waist circumference and blood pressure measured. Fasting plasma glucose (FPG), total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), and low density lipoprotein cholesterol (LDL-C)were measured in 962 subjects from one school. In 2013, by using the same sampling design, 7 211 students from two districts (Haidian and Dongcheng) were surveyed with weight, height, waist circumference and blood pressure measured, and fasting plasma glucose and lipid profile (TC, TG, HDL-C, LDL-C) were measured for 1 344 subjects in the same school measured in 2004. Student's-t test was used to analyze the difference in body mass index(BMI), WC, and waist to height ratio (WHtR) among children between 2004 and 2010. Chi-square test was used to analyze the difference of hypertension, impaired fasting glucose(IFG), dyslipidemia, and metabolic disorders clustering between 2004 and 2010, and among different types of obesity; logistic regression model was used to analyze the association between three types of obesity and risks of cardiovascular metabolic disorders. Results In boys, BMI ((20.3±4.4) vs (19.4±4.2) kg/m2, t=l 1.18, P〈0.001), WC ((70.6± 12.8) vs (66.7± 11.8) cm, t=17.20, P〈0.001) and WHtR (0.451 + 0.064 vs 0.437 ± 0.059, t=l 1.64, P〈0.001) were significantly higher in 2013 than those in 2004. Similarly in girls, BMI ((18.9±3.6) vs (18.7+3.7) kg/m2, t=12.21, P〈0.001), WC ((64.5±9.6) vs (63.0±9.3) cm, t=8.15, P〈0.001) and WHtR (0.430±0.047 vs 0.423±0.047, t=14.13, P〈0.001) were also significantly higher in 2013 than those in 2004. The prevalence of combined obesity rose from 8.27% (1 697/20 526) in 2004 to 10.74% (774/7 209) in 2013, and central obesity from 3.08% (632/20 526) to 4.44% (320/7 209). The prevalence of hypertension (10.78%(313/1 344) vs 4.29% (42/962), X%36.76, P〈0.001), IFG(49.54%(664/ 1 344) vs 6.45%(63/962), X2=506.61, P〈0.001), high TC(11.53%(155/1 344) vs 5.03%(49/962), X2=28.31, P〈 0.001), high TG(7.51%(101/1 344) vs 3.59%(35/962), X2=29.59, P〈0.001) were signifieantly higher in 2013 than those in 2004. Subjects with combined obesity had higher risks of hypertension (OR=5.88, 95% CI: 4.42 - 7.82), high TG (OR=7.12, 95%Ch 4.35 - 11.64), low HDL-C (OR=3.04, 95%CI: 1.55 - 5.95), high LDL-C (OR=2.27, 95% Ch 1.22 - 4.02), CDs≥2 (OR=3.07, 95% Ch 2.09 - 4.50), comparing to ehildren without obesity. Conclusion The prevalence of types of obesity and obesity-related metabolic disorders, except for low HDL-C and high HDL-C, were significantly higher in 2013 than those 2004 among chlildren aged 6 - 17 year in Beijing. Children with combined obesity had higher prevalence of metabolic disorders.
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
2016年第1期34-39,共6页
Chinese Journal of Preventive Medicine
基金
北京市科技计划重大项目(D111100000611002,D08050700320003)
“十二五”国家科技支撑计划(2012BA103803)
北京市教育委员会学生综合素质提升项目(京财教育指[2013]391号)
关键词
儿童
肥胖症
代谢
罹患率
横断面研究
Children
Obesity
Metabolism
Attack rate
Cross-Sectional studies