摘要
帕金森病(PD)早期可以出现非运动症状,而且有可能是最先出现的症状。与其运动症状一样,同样会促使病情进展,造成或加重病人的残疾。多模态MRI可以发现PD伴认知功能障碍病人、PD伴抑郁病人在脑结构、代谢及功能方面的改变,对PD非运动症状的诊断、疗效监测和预后评估具有重要的作用。
Parkinson＇s disease （PD） at early phase may appear non motor symptoms, and may even be the first symptoms. As the motor symptoms in PD, non motor symptoms may also promote the progress of the disease, causing or aggravating the patient＇s disability. Muhimodal magnetic resonance imaging can find the changes of brain structure, metabolism and function in PD with cognitive impairment or depression, which are crucial in diagnosis, therapeutic effect monitoring and prognosis prediction of non motor symptoms in PD.
出处
《国际医学放射学杂志》
2016年第1期10-12,共3页
International Journal of Medical Radiology
基金
国家自然科学基金(81471646)
湖南省自然科学基金(14JJ2027)
关键词
帕金森病
非运动症状
磁共振成像
痴呆
抑郁
Parkinson＇ s disease
Non motor symptoms
Magnetic resonance imaging
Dementia
Depression
