摘要
目的:观察独活寄生汤联合塞来昔布治疗膝骨关节炎的临床疗效。方法:将64例膝骨关节炎患者随机分为治疗组和对照组,每组32例。对照组给予塞来昔布每次200 mg,每日1次,口服;治疗组在对照组的基础上加用独活寄生汤加减治疗。30 d为1个疗程,共治疗2个疗程。观察2组临床疗效,采用WOMAC评估患者膝关节疼痛、僵硬及生活受限的程度。结果:治疗组显效1例,有效30例,无效1例,总有效率为96.88%;对照组显效0例,有效15例,无效17例,总有效率为46.88%。2组比较,差异有统计学意义(P<0.05)。治疗后,2组WOMAC评分较治疗前均有改善(P<0.05),且治疗组优于对照组(P<0.05)。结论:独活寄生汤联合塞来昔布治疗膝骨关节炎可有效提高临床疗效。
Objective：To observe the clinical curative effect of Duhuo Jisheng Tang （ 独活寄生汤） ） combined with celecoxib in the treatment of knee osteoarthritis.Methods：64 cases of knee osteoarthritis were randomly divided into two groups：a treatment group and a control group,32 cases in each.Each patient in the control group was orally given 200 mg of celecoxib,once a day;while those in the treatment group,based on the treatment of the control group were given modified Duhuo Jisheng Tang.There are 2 courses of treatment,30 days for each.The clinical curative effect of the 2 groups was observed and the WOMAC was used to evaluate the degrees of knee joint pain,stiffness,and limitation of life.Results：In the treatment group,1 case was markedly effective,30 cases were effective,and 1 case was ineffective,the total effective rate being 96.88%;while in the control group,no case was markedly effective, 15 cases were effective,and 17 cases were ineffective,the total efficiency being 46.88%.The difference between the two groups was statistically significant （P 〈 0.05 ） .After treatment,the WOMAC scores of the two groups were more improved than those before treatment （ P 〈 0.05 ）,and the treatment group was better than the control group （ P 〈 0.05 ） .Couelusion：Duhuo Jisheng Tang combined with celecoxib can effectively improve the clinical curative effect in the treatment of knee osteoarthritis.
出处
《风湿病与关节炎》
2016年第1期11-13,共3页
Rheumatism and Arthritis
关键词
骨关节炎
膝
独活寄生汤
塞来昔布
osteoarthritis,knee
Duhuo Jisheng Tang （ 独活寄生汤） ）
celecoxib
