摘要
目的分析127例血清淀粉样蛋白A（SAA）和C-反应蛋白（CRP）检测结果不一致病例。方法选择127例SAA增高而CRP正常及CRP增高而SAA正常的患者,分别对白细胞计数（WBC）、中性粒细胞比例（NEU%）、CRP和SAA四个指标进行检测及相关性分析。结果 SAA增高而CRP正常的118例患者中,WBC〉9.5×10^-9/L（A组）的SAA与CRP呈明显正相关（r=0.482,P〈0.01）;WBC在（3.5-9.5）×10^-9/L（B组）的SAA与CRP呈明显正相关（r=0.267,P〈0.05）,SAA与NEU%呈明显正相关（r=0.334,P〈0.01）;WBC〈3.5×10^-9/L（C组）的WBC、CRP和SAA三项之间均无相关性,但WBC与NEU%呈明显正相关（r=0.503,P〈0.05）;CRP增高而SAA正常的9例患者中,SAA与CRP呈正相关（r=0.842,P〈0.01）。结论临床上进行感染性疾病的快速诊断时,四个指标中任何一项均应认真结合临床做出判断,以免漏诊或误诊。
Objective To analyze the inconformity of serum amyloid protein A（SAA）and C reactive protein（CRP）detection results in 127 cases.Methods 127 cases of increased SAA with normal CRP and increased CRP with normal SAA were selected,and their WBC,NEU%,CRP and SAA were detected.The correlation of these four indexes was analyzed at the same time.Results Among 118 cases of increased SAA with normal CRP,there was significant correlation between SAA with CRP in the WBC9.5×10^9/L group（group A）（r=0.482,P〈0.01）,significant correlation between SAA with CRP and significant correlation between SAA with NEU% in the WBC（3.5-9.5）×10^9/L group（group B）（r=0.267,P〈0.05;r=0.334,P〈0.01）;WBC,CRP and SAA were uncorrelated with each other in the WBC3.5×10^9/L group（group C）,while WBC had significant correlation with NEU%（r=0.503,P〈0.05）.In 9cases of increased CRP with normal SAA,there was significant correlation between SAA with CRP（r=0.842,P〈0.01）.Conclusion In clinical rapid diagnosis of infectious diseases,any one item of these four indexes should be judged by carefully combining with clinic for avoiding missed diagnosis or misdiagnosis of infectious diseases.
出处
《检验医学与临床》
CAS
2016年第2期198-200,共3页
Laboratory Medicine and Clinic
