摘要
本研究利用具有反应活性的聚乙二醇对天然大分子壳聚糖进行化学改性,通过酰化反应合成了聚乙二醇-接枝-壳聚糖聚合物(PEG-g-CS)。采用FT-IR对PEG-g-CS的化学结构进行了分析和表征,结果表明PEG成功地接枝在了壳聚糖上。PEG修饰后的壳聚糖具有良好的水溶性,可以作为水性涂层对皮革表面进行抗菌整理。通过测定最小抑菌浓度及抑菌圈探索了该接枝共聚物的抗菌性能。抗菌结果表明,PEG接枝的壳聚糖将PEG的抑菌性和壳聚糖的杀菌性有机地协同起来,与单一的壳聚糖涂层对比表现出更优异的抗菌性能。
In this work, PEGylated chitosan was synthesized by conjugating PEG to the chitosan backbone.The synthetic process and structure of PEGylated chitosan were characterized by FT-IR. After PEGylation, the water solubility of chitosan was improved and such PEGylated chitosan could be used as water borne coatings for leather surface. The anti- microbial activity of PEGylated chitosan coating was investigated by measuring its minimum inhibitory concentration and the inhibition zone of coated leather sample. The result showed PEG modified chitosan exhibited better antibacterial property than that of chitosan, which indicated the synergetic antimicrobial effect of PEG and chitosan.
出处
《皮革科学与工程》
CAS
2016年第1期28-32,共5页
Leather Science and Engineering
基金
现代农业产业技术体系建设(CARS-44-D-3)
四川大学科研启动金(2014SCU11026)
国家自然科学基金(NSFC5103131)
中国博士后面上基金(2015M570783)
