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网织红细胞及红细胞相关参数在贫血鉴别诊断中的应用 被引量:18

Application of reticulocyte and red blood cell related parameters in differentiation diagnosis of anemia
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摘要 目的探讨网织红细胞参数联合红细胞参数在临床常见3种贫血鉴别诊断中的价值。方法检测3种贫血患者和体检健康者的红细胞相关参数MCV、MCH、MCHC、RDW-SD及网织红细胞相关参数RET%、RET#、IRF、LFR。结果与健康对照组比较,IDA组MCV、MCH、MCHC、LFR明显减低,RDW-SD、RET%、IRF明显增高;慢性病贫血组,MCHC、LFR明显减低,RED-SD、RET%、IRF明显增高;肾性贫血组MCV、MCH、MCHC、RET#、LFR明显减低,RDW-SD、IRF明显增高。缺铁性贫血组与慢性病贫血组比较,MCV、MCH、MCHC显著减低;缺铁性贫血组与肾性贫血组比较,MCV、MCH、MCHC、LFR显著减低,IRF显著升高;慢性病贫血组与肾性贫血组比较,MCHC、LFR显著降低,而RDW-SD、RET%、RET#、IRF显著升高。结论网织红细胞联合红细胞相关参数对3种类型贫血的鉴别诊断具有一定临床意义。 Objective To investigate the value of the parameters of reticulocyte(RET)and red blood cell(RBC)in the differentiation diagnosis of three kinds of clinical common anemia.Methods The RBC related parameters of MCV,MCH,MCHC and RDWSD,and the RET related parameters of RET%,IRF,RET# and LFR were detected in the patients with 3kinds of anemia.Results Compared with the control group,MCV,MCH,MCHC,LFR in the iron deficiency anemia(IDA)group were significantly decreased,while RDW-SD,RET% and IRF were significantly increased;MCHC and LFR in the anemia of chronic disease(ACD)group were significantly decreased,while RED-SD,RET% and IRF were significantly increased;MCV,MCH,MCHC,RET# and LFR in the renal anemia(RA)group were significantly decreased,while RDW-SD and IRF were significantly increased.In the comparison between the IDA group with the ACD group,MCV,MCH and MCHC were significantly decreased;in the comparison between the IDA group with the RA group,MCV,MCH,MCHC,LFR,IRF were significant decreased,while IRF was significantly increased;in the comparison between the ACD group with the RA group,MCHC and LFR were significantly decreased,while RDWSD,RET% and RET# and IRF were significantly increased.Conclusion The related parameters of RBC combined with RET have a certain clinical significance to the differentiation diagnosis of three types of anemia.
作者 张伟 丁大朋
出处 《国际检验医学杂志》 CAS 2016年第1期65-66,共2页 International Journal of Laboratory Medicine
关键词 网织红细胞参数 红细胞参数 缺铁性贫血 慢性病贫血 肾病性贫血 reticulocyte parameter red blood cell parameter the iron deficiency anemia anemia of chronic disease renal anemia
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