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关节健康、老化及骨关节中细胞自噬和软骨内稳态机制分析

Joint health and its aging process,autophagy in joint cells and stable internal conditions of arthrodial cartilage
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摘要 骨关节炎是最为常见的关节疾病,但却没有有效的预防措施和治疗该病的药物。由于以患者为对象的药物研究未能成功,人们逐渐开始关注维持关节健康的机制。增强该机制可能成为预防关节炎的新方法。现就维持细胞和组织稳态的机制及其衰退过程做一介评。增强该机制将作为延缓关节衰老以及降低关节炎风险的新方法加以讨论。 Arthritis is the most commonly seen joint disease,which does not have any effective prevention measures or therapeutic drugs.Alternatively,people have started focusing on the mechanisms that help to maintain healthy joints after failing to discover effective drugs for the patients;such mechanisms will probably become new prevention measures for arthritis.This article reviews the mechanisms that maintain cells and tissues in stable condition,and ways to delay the joint aging process and to lower risks of arthritis.
作者 郝婧灿 张峰
出处 《国外医学(医学地理分册)》 CAS 2015年第4期257-258,273,共3页 Foreign Medical Sciences:Section of Medgeography
基金 国家自然科学基金资助项目(No.81102086)
关键词 关节软骨 浅表层 自噬 衰老 关节炎 arthrodial cartilage superficial layer autophagy aging arthritis
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参考文献9

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