摘要
[目的]探讨联合检测血清中C反应蛋白（CRP）和降钙素原（PCT）在急性胰腺炎（AP）中的临床诊断价值。[方法]选择我院2012年2月~2015年2月符合入选标准的101例AP患者作为研究对象。根据病情将患者分为感染组25例和非感染组76例。动态观察患者第1、3、7、14天血清中CRP和PCT的变化趋势,并统计CRP和PCT联合检测及单独检测对AP诊断的敏感性和特异性。[结果]感染组患者第1、3、7、14天的血清中CRP和PCT水平均明显高于非感染组患者,差异有统计学意义（P〈0.05）;联合检测CRP和PCT对AP早期诊断的敏感性为90.1%,特异性为90.8%,比CRP、PCT单独检测的敏感性（80.5%、77.9%）和特异性（84.9%、83.4%）明显增高（P〈0.05）。[结论]联合检测血清中CRP和PCT的变化有助于早期诊断AP并发的感染,为其诊断、分类以及早期治疗提供有效的依据。
[Objective]To investigate the value of combined detection of C-reactive protein（CRP）and Procalcitionin（PCT）for early diagnosis of acute pancreatitis（AP）.[Methods]One hundred and one cases of patients from February 2012 to February 2015 were divided into the infection necrotic pancreatitis group（the INP group,25cases）and non infection necrotic pancreatitis group（the NINP group 76cases）.The change of serum CRP and PCT were observed in d1,d3,d7,and d14.The correlation of CRP and PCT together or alone with the sensitivity and specificity of AP diagnosis was analysed.[Results]The levels of CRP and PCT in the INP group in d1,d3,d7,and d14 were higher than the NINP group.The differences were statistically significant（P〈0.05）.The sensitivity of combined detection of CRP and PCT for early diagnosis of AP was 90.1%,and the specificity was 90.8%,which were significantly higher than the sensitivity（80.5%,77.9%）and specificity（84.9%,83.4%）of the separate detection of CRP and PCT（P〈0.05）.[Conclusion]Combined detection of CRP and PCT is helpful for early diagnosis of AP complicated infection,and provide evidence for its early diagnosis.
出处
《中国中西医结合消化杂志》
CAS
2015年第12期878-880,884,共4页
Chinese Journal of Integrated Traditional and Western Medicine on Digestion
关键词
C反应蛋白
降钙素原
急性胰腺炎
感染
联合检测
C-reactive protein
procalcitionin
acute pancreatitis
infection
combined detection
