摘要
帕金森病(PD)是一种常见的神经系统变性疾病。PD患者除了静止性震颤、肌强直、运动迟缓和姿势步态异常等运动症状外,还可出现焦虑、抑郁、睡眠障碍、认知功能障碍、胃肠功能障碍等非运动症状。胃肠功能障碍,尤其是便秘,影响患者的生活。PD患者便秘的发病机制及病理生理机制目前仍不明确,治疗便秘方案多种多样。文中就近期PD便秘的病理生理机制及相关治疗研究进行综述。
Parkinson＇s disease （PD） is a common neurodegenerative disease. Apart from motor symptoms like static tremor, rigidity, bradykinesia and postural gait abnormality, patients with PD also have some non-motor symptoms, such as anxiety, depression, sleep disorders, cognitive disorders, gastrointestinal dysfunction, etc. Gastrointestinal dysfunction, especially constipation, affects the life of patients. The pathogenesis and pathophysiological mechanisms of Parkinson＇s disease are not clear. There is a variety of treatments for constipation. The pathophysiological mechanism and the related treatments in the near future were reviewed.
出处
《中国临床神经科学》
2015年第6期711-714,共4页
Chinese Journal of Clinical Neurosciences
关键词
帕金森病
便秘
病理生理机制
治疗
Parkinson＇s disease
constipation
pathophysiologicalmechanisms
treatment
