摘要
埃博拉出血热(EHF)临床可出现高热、休克、凝血机制异常、急性肝功能衰竭、急性肾功能衰竭等严重并发症。EHT病情变化迅速,病死率高。随着病情的进展,还可导致一系列神经精神症状(如抽搐、听力减退、视力减退、头晕、头痛、神经性厌食症、抑郁、睡眠障碍、焦虑、易怒等)。相对于其他临床表现,EHF的神经精神症状较少见,因其主要出现于患者的病程终末期或幸存者中,严重影响患者的预后及生活质量,故值得神经科医生关注。文中报道EHF的神经精神症状及相关病理变化。
Ebola hemorrhagic fever （EHF） is a severe syndrome with rapid progression and high mortality, manifesting hyperpyrexia, shock, abnormal blood coagulation mechanism, acute liver and kidney injury. As the disease progresses, patients may show some symptoms of central nervous system, such as convulsion, hearing vision loss, headache, dizziness, anorexia, depression, sleep-disorder, anxiety and irritability. In contrast with other symptoms, the neuropsychiatric symptoms tend to emerge gradually in the end-stage on critical patients or the survivors, suggesting the severe prognosis and bad quality of life. Therefore, it is of great necessity for neurologists to learn more about the pathology and symptoms induced by Ebola virus. In this review, the neuropsychiatric symptoms and the pathology were discussed.
出处
《中国临床神经科学》
2015年第6期683-687,共5页
Chinese Journal of Clinical Neurosciences
关键词
埃博拉出血热
埃博拉病毒
神经精神症状
病理
Ebola hemorrhagic fever
Ebola virus
neuropsychiatric symptoms
pathology
