摘要
目的探讨β_2受体激动剂与抗胆碱能药物治疗慢性阻塞性肺疾病的临床疗效及药学分析。方法选取2014年3月~2015年3月在我院呼吸内科接受治疗的122例慢性阻塞性肺疾病患者作为实验对象,按照治疗方法不同将其分为实验组和对照组,对照组患者给予常规对症治疗,实验组患者在对照组治疗基础上采取沙丁胺醇气雾剂与异丙托溴铵气雾剂进行治疗,并比较两组患者临床效果及肺功能改善情况。结果经过治疗后,对照组患者治疗总有效率为72.1%（44/61）,实验组患者治疗总有效率为93.4%（57/61）,对照组患者治疗有效率显著低于对照组,两组治疗有效率比较差异具有统计学意义（P〈0.05）;同时与对照组患者比较,实验组患者肺功能得到显著改善,两组比较差异具有统计学意义（P〈0.05）。结论β_2激动剂联合抗胆碱药物在治疗慢性阻塞性肺疾病方面临床效果显著,且可显著改善患者肺部功能,该方法具有临床推广应用价值。
Objective To investigate the clinical effect of the treatment of chronic obstructive pulmonary disease（COPD） with β_2 adrenergic receptor agonists and anticholinergic, and make pharmaceutical analysis of the medicine. Methods 122 cases of patients with COPD received treatment in our hospital＇s respiration medicine department from March 2014 to March 2015 were selected as experimental objects. According to different treatment regimens, they were divided into an experimental group and a control group. The control group was given conventional symptomatic treatment, while the experiment group was given Salbutamol Aerosol and Ipratropium Bromide Aerosol on the basis of the treatment that the control group received. The clinical effect on the two groups and improvement of the pulmonary function of the two groups were compared. Results After treatment, the effective rate of the treatment in the control group was 72.1%（44/61）; the effective rate of the treatment in the experimental group was 93.4%（57/61）. the effective rate of the control group was significantly lower than that of the experimental group, the difference in the comparison of effective rate of the two groups was statistically significant（P〈0.05）; meanwhile, in comparison with the control group, the improvement of pulmonary function of the experimental group was significant, the difference between the two groups was statistically significant（P〈0.05）. Conclusion The clinical effect of β_2 adrenergic receptor agonists and anticholinergic in the treatment of COPD is significant, and the treatment also can improve the pulmonary function of the patient significantly, therefore, this regimen has application value in clinical practice.
出处
《中国医药科学》
2015年第21期101-103,共3页
China Medicine And Pharmacy
关键词
β_2受体激动剂
抗胆碱药物
慢性阻塞性肺疾病
临床效果
β_2 adrenergic receptor agonists
Anticholinergic
Chronic obstructive pulmonary disease
Clinical effect
