摘要
Visual disorders may occur in Neuroborreliosis, Multiple Sclerosis, and many other diseases. The aim of this work was to find electro-physiological cues for differentiation. The study was based on the investigation of 178 patients presenting visual disorders. Out of them 57 were affected by Neuroborreliosis （demonstrated by positive serologic investigation： Western Blot and immuno-assay）. The electro-physiological research consisted in Electroencephalography （EEG） Mapping and average Visual Evoked Potentials （VEPs） investigation. Characteristic for the Lyme disease was the non-homogenous slowing of the cortical electrical activity, associated with signs of excessive cortical excitability to flash stimulation. In Multiple Sclerosis （MS） there were no similar changes, but signs of sub-cortical white matter lesions. Primary cortical VEP components were significantly attenuated in amplitude in the Lyme disease and delayed in MS. Magnetic Resonance Imaging （MRI） showed the presence of not differentiated ＂demyelization lesions＂ in all these cases. The electro-physiologic investigation confirms the existence of cerebral （cortical） dysfunction in subjects serologically confirmed with Borrelia infection. It may be used in time for the follow up of the Lyme disease patients.
