摘要
目的:比较糖尿病与非糖尿病患者尿路感染的临床特点、病原菌及药敏结果,协助临床合理使用抗生素。方法:收集2014年1月至2015年1月我院确诊为尿路感染的住院患者947例,根据有无合并糖尿病,设合并糖尿病为观察组,共153例,非糖尿病患者为对照组,共794例。通过病例对照研究2组的临床情况、病原菌分布及药敏情况。结果:观察组的无症状性菌尿占22.2%,分离的病原菌排前3位的依次为大肠埃希菌、奇异变形杆菌、肺炎克雷伯菌。对照组的无症状性菌尿占12.0%,分离病原菌排前3位的为大肠埃希菌、肺炎克雷伯菌、肠球菌。观察组检出的大肠埃希菌对氨曲南、阿米卡星较对照组敏感性低,差异有统计学意义(P<0.05)。结论:糖尿病患者无症状性菌尿发生率高,隐匿起病,因此要重视糖尿病患者中段尿的培养及监测。
[Objective] To study the clinical features,distribution of pathogens and their sensitivities to antibioticsinof diabetic and non- diabetic patients w ith urinary tract infections,and to provide the basis for clinical diagnosis and rational use of antibiotics. [Method]947 cases w ith urinary tract infection w ere collected in our hospital from January 2014 to January 2015,and w ere divided into tw o groups according to w ith or w ithout diabetes. The observational group contained153 diabete cases w hilethecontrol group contained 794 non- diabete cases. Then the clinical features,distribution of pathogens and sensitivities to antibiotics w ere investigated in the tw o groups. [Result] The morbidity ofasymptomatic bacteriuria in observational group w as 22. 2%,and the top three pathogens isolated from the urine w ere Escherichia coli,Proteus mirabilis,Klebsiellapneumonia,w hile the morbidity in control w as 12. 0%,and the top three pathogens w ere Escherichia coli,Klebsiellapneumoniae,Enterococcus. The susceptibility rates of Escherichia coli to aztreonam,amikacinin the observation group w ere low er than in the control group（ P〈0. 05）. [Conclusion]The morbidity of asymptomatic bacteriuriainin diabetic patients w as higher than that in non- diabetic patients,w hichocculted onset easily. Therefore,w e should pay attention to the bacterial culture and monitoring of midstream urine in patients w ith diabetes.
出处
《浙江医学教育》
2015年第6期54-57,共4页
Zhejiang Medical Education
基金
温州市科学技术局项目(编号:Y20120116)
关键词
糖尿病
尿路感染
非糖尿病
病原菌
diabetes
urinary tract infection
non-diabetes
pathogens
