摘要
目的：探究近5年来上尿路结石患者尿液中细菌阳性率及细菌种类分布,并对其中的性别差异进一步探讨。方法：选取2010-2014年我院泌尿外科诊断为泌尿系上尿路结石的2536例住院患者,回顾性调查其入院时所行的尿培养检测结果,统计这5年内尿培养的阳性率、常见的细菌种类、性别差异与尿液细菌的关系等。结果：上尿路结石患者尿液细菌阳性率在20%-40%,近年来有所下降（P〈0.05）;其中,大肠埃希菌仍为主要的菌种（总阳性率46.37%）,粪肠球菌的感染率也逐年上升（由2010年的阳性率1.33%上升至2014年的6.64%）,现成为仅次于大肠埃希菌的第2位感染细菌。在男女性别差异方面,女性患者的尿路感染率以及大肠埃希菌阳性率明显高于男性患者（P〈0.05）。结论：随着医院感染控制措施的加强以及抗生素的应用,上尿路结石患者的尿路感染率逐步下降,而大肠埃希菌的阳性率仍居高不下,近年来粪肠球菌的感染也应重视。相对于男性患者,女性患者更应注意预防感染、合理应用抗生素。
Objective： To explore the urine bacteria in the patients with upper urinary stones in recent five years including the bacterial positive rate and bacterial species distribution, and compare the gender difference. Method： The data of 2 536 patients with upper urinary stones from January 2010 to December 2014 in our hospital were analyzed, and the urine culture results and the positive rate, bacterial species, gender difference, etc were retrospectively studied. Result： The urine bacteria positive rate ranged from 20% to 40%, but in recent years there has been a tendency to decline （ P 〈0.05）. E. coli was still the main kind, and the whole positive rate was 46.37%. The rate of Enteroeoceus faecalis rose year by year from 1.33% in 2010 to 6.64% in 2014, and now it become the bacteria infection second to E. coli. In terms of gender difference, females with urinary tract infection and their positive rate of E. coli were significantly higher than those of males （ P 〈0.05）. Conclusion： With the concentration of hospital infection control measures and the application of antibiotics, patients with upper urinary stones have a decreasing urinary tract infection rate, but the positive rate of E. coli is still high. However, Entero- coccus faecalis infection also should be paid more attention. Compared with male patients, female patients should be more careful to prevent infection and use antibiotics reasonablely.
出处
《临床泌尿外科杂志》
2015年第12期1092-1095,共4页
Journal of Clinical Urology
基金
卫生部国家临床重点专科建设项目(2012)
国家自然科学基金项目(编号81170698
81370856)
安徽省自然科学基金项目(编号1508085MH177)
关键词
上尿路结石
尿路感染
大肠埃希菌
性别差异
upper urinary stones
urinary tract infection
E. coli
gender difference
