摘要
目的研究弥散张量成像（DTI）在高血压性脑出血（HICH）后皮质脊髓束（CST）损伤中的应用价值。方法选择2013年1月至2015年5月接受诊治的HICH患者82例进行研究,分别在入院时及3个月后对所有患者进行DTI检查,对比患者不同时期的部分各向异性（FA）值、表观弥散系数（ADC）值比率,肌力及NHISS评分,分析FA值、ADC值比率与肌力及NHISS评分的相关性。结果患者发病3个月后肌力4~5级组的FA值比率显著高于肌力1~3级组,差异有统计学意义（P〈0.05）。发病3个月后CST完整组的肌力显著高于CST中断组,神经功能缺损（NHISS）评分显著低于CST中断组,差异有统计学意义（P〈0.05）。根据Pearson法分析相关性可知,患者FA值比率与肌力呈正相关,与NHISS评分呈负相关。ADC值比率与肌力及NHISS评分则无明显相关性。结论 DTI可较好地反映HICH患者的CST损伤情况,对患者的诊断与治疗具有积极的辅助作用。
Objective To study the application value of diffusion tensor imaging（ DTI） in corticospinal tract（ CST） injury after hypertensive intracerebral hemorrhage（ HICH）. Methods From January 2013 to May 2015 in our hospital,82 patients with HICH were studied. DTI was performed in all patients at admission and 3 months after admission. The fractional anisotropy（ FA） ratio,apparent diffusion coefficient（ ADC） ratio and NHISS scores were compared between the patients with different periods,the correlation between FA,ADC,FA and NHISS score was analyzed. Results The FA ratio of the muscle strength grade 4 ~ 5 group was significantly higher than that of the muscle strength grade 1 ~ 3 group after the onset of 3 months. The difference was statistically significant（ P 〈 0.05）. After 3 months,the muscle strength of the CST complete group was significantly higher than that of the CST interrupt group,and the NHISS score was significantly lower than that in the CST interrupt group,the difference was statistically significant（ P 〈 0.05）. According to the Pearson correlation analysis,the ratio of FA was positively correlated with the muscle strength,but negatively correlated with NHISS score. ADC ratio was not correlated with muscle strength or NHISS score. Conclusion DTI can reflect CST damage of HICH patients,and it has a positive effect on the diagnosis and treatment of patients.
出处
《临床和实验医学杂志》
2015年第24期2089-2091,共3页
Journal of Clinical and Experimental Medicine
关键词
高血压性脑出血
皮质脊髓束损伤
弥散张量成像
Hypertensive cerebral hemorrhage
Corticospinal tract injury
Diffusion tensor imaging
