摘要
目的探讨强化极化液联合环磷腺苷葡胺治疗慢性心衰的临床效果。方法将慢性心力衰竭患者96例,按治疗方法不同分为对照组(使用强化极化液)和观察组(强化极化液联合环磷腺苷葡胺)各48例,比较两组治疗总有效率、治疗前后心输出量及左心室射血分数。结果观察组显效18例,有效27例,无效3例,对照组显效11例,有效27例,无效10例,观察组治疗总有效率为93.75%(45/48),明显高于对照组79.17%(38/48)(P<0.05);治疗后,观察组平均心输出量及左心室射血分数均高于对照组(45/48),两组比较,差异均有统计学意义(P均<0.05)。结论环磷腺苷葡胺联合强化极化液治疗慢性心力衰竭能显著改善患者生命体征,缓解临床症状,疗效好,值得应用于临床。
Objective To explore the clinical effect of strengthened glucose-insulin-potassium solution （strengthened GIK） combined with meglumine cyclic adenylate （MCA） in the treatment of chronic heart failure. Methods Ninety-six patients with chronic heart failure admitted to our hospital were divided into control group （enhanced GIK） and observation group （GIK plus MCA）. The total effective rate, cardiac output and left ventricular ejection fraction （LVEF） were compared between groups. Results In observation group, the numbers showing remarkable effect, effect, and no effect were 18, 27, and 3 respectively. In control group, the numbers showing remarkable effect, effect, and no effect were 11,27, and 10 respectively. The total effective rate in the observation group was 93.75%, significantly higher than that in the control group （79.17%）, and so were the mean cardiac output and LVEF. Conclusion Strengthened GIK） combined with MCA in treating chronic heart failure, can significantly improve the vital signs, relieve symptoms, worthy of clinical application.
出处
《微创医学》
2015年第5期571-573,共3页
Journal of Minimally Invasive Medicine
基金
广西自然科学基金(编号:2012GXNSFAA053090)
关键词
慢性心力衰竭
强化极化液
环磷腺苷葡胺
临床疗效
Chronic heart failure
Strengthened GIK
Meglumine cyclic adenylate
Clinical effect
