摘要
目的比较纱布与泡沫辅料填充伤口实施负压治疗对伤口组织血管化形成的影响与作用。方法随机选取该院自2012年9月—2014年9月收治的60例接受伤口负压治疗的患者作为研究对象,随机将其分为A、B两组,每组30例。A组患者采用泡沫敷料,B组则应用纱布辅料,两组均接受负压治疗,智能化吸引装置参数设置一致,比较两组患者伤口血管组织化形成指标的变化情况。结果治疗前及治疗1周、2周、3周后,两组患者CD34+血管内皮细胞数量及PCNA对比差异均无统计学意义(P>0.05)。结论在慢性伤口患者的负压填充治疗中,无论采用纱布或泡沫作为填充敷料,均不会对伤口组织血管化及组织增殖活性造成影响。采取负压填充治疗可促进患者伤口组织血管化的形成,提升细胞增殖活性,促进伤口愈合。
Objective To compare the effect of negative-pressure wound therapy （NPWT）using gauze and foam on the form of wound tissue vascularization. Methods 60 cases of patients admitted into the hospital from September 2012 to September 2014 for negative pressure wound therapy were selected as the research object and they were randomly divided into A, B two groups with 30 cases in each group. Group A was treated with foam dressing while group B with gauze. Two groups were treated with negative pressure therapy; the parameter settings of intelligent suction devices were consistent. Changes of the indexes of wound vascular tissue formation of two groups were compared. Results Before the treatment and 1 week, 2 weeks, 3 weeks later, the contrast differences of the number of CD34＋vascular endothelial cells and PCNA were of no statistical significance （P〉0.05）. Conclusion No matter using gauze or foam dressing as filler in the treatment of negative pressure filling of patients with chronic wound, there will be no influence. To adopt the negative pressure filling treatment can promote the formation of patients wound tissue vascular, enhance the activity of cell proliferation and promote wound healing.
出处
《中外医疗》
2015年第18期70-71,共2页
China & Foreign Medical Treatment
关键词
伤口
纱布
泡沫
敷料
负压治疗
血管化
Wound
Gauze
Foam
Dressing
Negative pressure therapy
Vascularization
