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利伐沙班中国研究现状与进展 被引量:3

Current status and progress in research of rivaroxaban in China
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摘要 临床上,抗凝药物被广泛用于血栓栓塞疾病的预防和治疗,包括深静脉血栓、肺栓塞、非瓣膜性房颤和急性冠状动脉综合征等。目前常用的传统抗凝药物包括低分子肝素和华法林,二者在临床长期应用时都各自存在问题。华法林是我国最常用口服抗凝药物,该药物药代动力学和药效动力学指标难以预测,治疗窗窄,易受多种食物、药物影响,故需频繁监测并调整药物剂量,为实际临床应用带来诸多困难。
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2015年第12期1047-1050,共4页 Chinese Journal of Practical Internal Medicine
关键词 利伐沙班 抗凝治疗 药物代谢动力学 药效动力学 rivaroxaban anticoagulant therapy pharmacokinetics pharmacodynamics
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参考文献20

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