摘要
目的探讨通腑净化汤联合西医常规方法治疗严重骨创伤后肠功能障碍的疗效。方法选择80例严重骨创伤后肠功能障碍的患者为研究对象,并随机均分为2组。治疗组40例,给予通腑净化汤联合西医常规方法,对照组40例,给予西医常规治疗。1周后对比2组患者的消化道体征发生率及血浆D-乳酸水平的情况。结果治疗组的消化道体征发生率低于对照组,差异有统计学意义(12.50%vs 35.00%,χ2=10.727,P<0.05);治疗组血浆D-乳酸水平低于对照组,差异有统计学意义(0.18±0.03 vs 0.28±0.04,t=12.649,P<0.05)。结论通腑净化汤联合西医常规方法通过改善肠黏膜屏障功能,治疗严重骨创伤后肠功能障碍。
Objective To investigate the effect of combined with western medicine routine treatment of severe bone trauma of intestinal barrier dysfunction. Methods The 80 patients cured with severe bone trauma of intestinal barrier dysfunction were chosen. All the cases were randomly divided into 2 groups, the treatment group including 40 cases and the control group including 40 cases. The treatment group received Tongfu Jinghua decoction combined with west- ern medicine routine treatment, while the control group received western medicine routine treatment. After intervention for one week, the incidence of gastrointestinal signs and plasma D-lactic acid in two groups were compared. Results The incidence of gastrointestinal signs in the treatment group were lower than the control group, the difference was sta- tistically significant （ 12.50% vs 35.00% , X2 = 10. 727,P 〈 0.05 ） ;The level of plasma D-lactic acid in the treatment group were shorter than the control group, the difference was statistically significant （0.18± 0.03 vs 0.28±0.04, t = 12. 649,P 〈 0.05 ）. Conclusion Tongfu Jinghua decoction combined with western medicine routine treatment is ben- eficial to the intestinal barrier dysfunction of patients with severe bone trauma.
出处
《吉林中医药》
2015年第11期1126-1128,共3页
Jilin Journal of Chinese Medicine
基金
山东省科技攻关计划资助项目(2007GG10002009)
关键词
通腑净化汤
骨创伤
肠功能障碍
通里攻下
清热解毒
活血化瘀
Tongfu Jinghua decoction
severe bone trauma
intestinal barrier dysfunction
expelling pathogens by purgation
clearing heat and removing toxicity
promoting blood circulation to remove blood stasis
