摘要
目的本研究旨在观察孕育口服液预防性治疗复发性流产脾肾两虚证患者的临床疗效。方法将脾肾两虚证复发性流产患者共61例,随机分为治疗组31例和对照组30例。治疗组于非月经期口服孕育口服液,对照组接受去T淋巴细胞主动免疫治疗。观察2组的封闭抗体转阳率,中医证候减少率及孕后胎漏、胎动不安复发率。结果研究结果显示,治疗组封闭抗体总转阳率为58.06%,对照组为76.67%,2组封闭抗体总转阳率无统计学意义(P>0.05);治疗组中医证候减少总有效率为90.32%,对照组56.67%,2组对比有显著统计学意义(P<0.01);随访治疗组孕后胎漏、胎动不安的复发率为11.11%,较对照组(36.00%)降低,二者有统计学意义(P<0.05);治疗组妊娠成功率77.78%,对照组48.00%,2组数据有统计学意义(P<0.05)。结论口服孕育口服液可促进封闭抗体转阳,疗效与去T淋巴细胞主动免疫相当,可明显改善RSA患者中医脾肾两虚证候,有利于妊娠维持,提高妊娠成功率。
Objective This study was designed to investigate the clinical efficacy of preventive oral inoculation with recurrent spontaneous abortion both spleen and kidney patients. Methods The spleen deficiency of both recurrent spontaneous abortion altogether 61 cases,31 cases were randomly divided into treatment group and control group of 30 patients treated for non-menstrual period oral conceived oral control group received active immunotherapy to Tlympho- cytes. Were observed blocking antibody positive rate of turn, reduce the rate syndromes, abortion after pregnancy, fetal movement disturbed recurrence rate. Results The results showed that the treatment group total turn blocking antibody positive rate was 58.06% ,the control group was 76.67% , the two groups total turn blocking antibody positive rate was no statistical significance （P 〉 0.05 ）, treatment group syndromes reduce the total effective rate 90.32% ,56.67% in the control group, there are between two groups was statistical significance （P 〈 0.01 ） , abortion, fetal irritability recur- rence rate was 11.11%, compared with the control group （36.00%） lower pregnancy follow-up treatment group, both have statistical significance （P 〈 0.05） , treatment group 77.78% pregnancy success rate,48.00% in the control group ,two sets of data were statisticalsignificance （P 〈 0.05 ）. Conclusion Liquid oral inoculation couldpromote blocking antibodies turn positive, efficacy and fairly active immunization to Tlymphocytes, can significantly improve the TCM spleen deficiency syndrome RSA two patients, help to maintain the pregnancy to improve pregnancy success rate.
出处
《吉林中医药》
2015年第11期1122-1125,共4页
Jilin Journal of Chinese Medicine
基金
2013年广东省中医药管理局立项项目(20132045)
关键词
孕育口服液
去T淋巴细胞主动免疫
同种免疫
封闭抗体
复发性流产
inoculation oral liquid
T lymphocyte active immune
isoimmunization
antiphospholipid antibody, APLA
recurrent spontaneous abortion
