摘要
目的探讨卡前列素氨丁三醇与缩宫素治疗宫缩乏力性产后出血的临床疗效。方法选择2008年1月—2015年2月收治的182例宫缩乏力性产后出血患者作为研究对象,随机分为对照组和观察组各91例。对照组采用缩宫素治疗,观察组采用卡前列素氨丁三醇联合缩宫素治疗。比较两组患者治疗效果、产后出血量及不良反应发生情况。计量资料采用t检验,计数资料采用χ2检验,P<0.05为差异有统计学意义。结果观察组总有效率为94.51%,高于对照组的38.46%,差异有统计学意义(P<0.05)。观察组治疗后10、30 min出血量及总出血量、治疗后出血量分别为(56.1±13.1)、(78.3±12.4)、(421.0±71.0)、(101.2±15.3)ml,低于对照组的(156.0±23.5)、(253.1±13.1)、(610.2±85.1)、(289.0±22.7)ml,差异均有统计学意义(均P<0.05)。观察组不良反应发生率为7.7%,低于对照组的17.6%,差异有统计学意义(P<0.05)。结论在严格掌握适应证的情况下,采用卡前列素氨丁三醇与缩宫素治疗产后宫缩乏力性出血疗效好、不良反应小,使用方便,值得临床推广应用。
Objective To investigate the clinical effect of carboprost tromethamine and oxytocin in the treatment of postpartum hemorrhage caused by uterine inertia. Methods 182 cases of uterine atony postpartum hemorrhage patients from January 2008 to February 2015 were selected and randomly divided into control group and observation group（ n = 91）. The patients in control group were treated with oxytocin, the patients in observation group were treated with carboprost tromethamine on the basis of control group. The clinical effect,volume of postpartum hemorrhage and incidence of adverse reaction were compared. Measurement data was processed by t test,count data was processed by chi square test,P 〈0. 05 was considered statistically significant. Results The total effective rate in observation group was 94. 51%,higher than that in the control group（ 38. 46%）,the difference was statistically significant（ P 〈0. 05）. The amount of bleeding after 10,30 min,the amount of bleeding,the amount of bleeding after treatment were（ 56. 1 ± 13. 1）,（ 78. 3 ± 12. 4）,（ 4. 21 ± 71.0）,（ 101. 2 ± 15. 3） ml,lower than that of the control group（ 156. 0 ± 23. 5）,（ 253. 1 ± 13. 1）,（ 610. 2 ± 85. 1）,（ 289. 0± 22. 7） ml,the differences were statistically significant（ all P 〈0. 05）. The incidence rate of adverse reactions in observation group was 7. 7%,which was lower than that in control group（ 17. 6%）,the difference was statistically significant（ P 〈0. 05）. Conclusions In strictly controlled indications,by card carboprost tromethamine and oxytocin in treating uterine atony postpartum hemorrhage has the advantages of good curative effect,less side effects,easy to use,it is worth of clinical application.
出处
《社区医学杂志》
2015年第22期26-28,共3页
Journal Of Community Medicine
关键词
卡前列素氨丁三醇
缩宫素
产后出血
Carboprost tromethamine
Oxytocin
Postpartum hemorrhage
