摘要
建立了高效液相色谱-蒸发光散射检测法测定右旋酮洛芬氨丁三醇注射液中的葡辛胺。采用Agilent Zorbax C18柱,以水（冰乙酸调至p H 3.5）∶乙腈为流动相,梯度洗脱,以蒸发光散射检测器检测。葡辛胺在0.005~0.25 mg/ml范围内线性关系良好。平均回收率为98.4%,RSD为1.1%。
An HPLC-ELSD method was established for the determination of N-octyl-D-glucamine in dexketoprofen trometamol injection. An Agilent Zorbax C18 column was used, with the mobile phase of water （adjusted to pH 3.5 by glacial acetic acid） ： acetonitrile by gradient elution. An evaporative light scattering detector was used. It was linear for N-octyl-D-glucamine in the range of 0.005 - 0.25 mg/ml. The average recovery was 98.4%, with RSD of 1.1%.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2015年第11期1227-1229,共3页
Chinese Journal of Pharmaceuticals
