摘要
目的分析腹腔镜胃穿孔修补术患者围术期细胞因子及疼痛相关血清指标变化。方法胃穿孔修补术患者58例，随机分为对照组和观察组，各29例，对照组予开腹手术治疗，观察组予腹腔镜手术治疗，检测两组手术患者术前及术后第1、3及7天细胞因子及疼痛相关血清指标，并比较其差异。结果术前两组的细胞因子及疼痛相关血清指标差异均无统计学意义（P〉O．05），观察组术后第1、3及7天的血清指标均好于对照组，且观察组术后第3天的细胞因子及术后第1天的疼痛相关指标均差于其他时间段（P〈0．05）。结论腹腔镜胃穿孔修补术患者围术期细胞因子及疼痛相关血清指标变化明显小于开腹手术，应针对其此种变化给予监测及干预。
Objective To study and observe the change situation of cytokines and pain related serum indice of patients with laparoscopic repair of gastric perforation during the perioperative period. Methods 58 patients with gastric perforation who were treated with repair operation in our hospital from February 2014 to February 2015 were the study object, and 58 cases were divided into control group and observation group with 29 cases in each group by the principle of random allocation, the control group were treated with open operation, the observation group were treated with laparoscopic operation, then the cytokines and pain related serum indexes of two groups before the operation and at first, third and seventh day after the operation were detected, and the detection levels of two groups at different time were compared. Results The cytokines and pain related serum indexes of two groups before the operation had no significant differences, all P〉0.05, while the serum indexes of observation group at first, third and seventh day after the operation were all better than those of control group, and the cytokines at third day after the operation and pain related serum indexes at first day aRer the operation of observation group were all worse than those at other times, all P〈0.05, the differences were significant. Conclusion The change of eytokines and pain related serum indexes of patients with laparoseopic repair of gastric perforation during the perioperative period are obviously smaller than those of open operation, and the change should be paid to monitoring and intervention.
出处
《浙江临床医学》
2015年第11期1859-1860,共2页
Zhejiang Clinical Medical Journal
关键词
腹腔镜胃穿孔修补术
围术期
细胞因子
疼痛相关血清指标
Laparoscopic repair of gastric perforation Perioperative period Cytokines Pain related serum indexes
