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缺血性脑卒中早期使用小牛血清去蛋白注射液的临床疗效 被引量：11

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摘要 目的:观察缺血性脑卒中发病早期(<12h)使用小牛血清去蛋白注射液的近远期疗效。方法:选取急性缺血性脑卒中患者102例,随机分为治疗组和对照组。2组采取相同的基础治疗,治疗组在此基础上加用小牛血清去蛋白注射液30ml/(d·次),静脉注射,连续给药4周。观察用药14d和28d的NIHSS评分、MMSE评分;治疗前和治疗后3d局部照影剂平均通过时间(r MTT)>145%的面积;治疗前和治疗后3d、7d血清神经元特异性烯醇化酶(NSE)水平。结果:在用药14d和28d后,治疗组NIHSS评分显著低于对照组(P<0.05),而用药后28d治疗组MMSE评分显著高于对照组(P<0.05)。用药后3d治疗组的r MTT>145%的面积显著低于对照组(P<0.05);用药后3d和7d治疗组的血清NSE水平显著低于对照组(P<0.05)。结论:缺血性脑卒中发病早期使用小牛血清去蛋白注射液,能够有效抢救缺血半暗带,降低缺血区域的神经元损伤,疗效显著。
作者 陆红
机构地区 锦州市中心医院神经内科
出处 《中日友好医院学报》 2015年第5期302-304,共3页 Journal of China-Japan Friendship Hospital
关键词 小牛血清去蛋白注射液 缺血性脑卒中 血清神经元特异性烯醇化酶 缺血半暗带
分类号 R743.3 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献17

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二级参考文献57

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共引文献132

同被引文献70

引证文献11

二级引证文献26

中日友好医院学报
2015年 第5期

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