摘要
目的分析伏立康唑联合康艾注射液治疗肺癌患者肺部真菌感染的效果评价,为有效治疗肺部真菌感染提供依据。方法选取医院2013年6月-2015年3月肺部真菌感染肺癌患者132例,按照入院顺序以及治疗方式的不同分为观察组和对照组各66例,观察组给予伏立康唑联合康艾注射液治疗,对照组给予伏立康唑治疗,分析比较两组患者治疗的各项指标。结果观察组在体温、白细胞恢复和住院时间均短于对照组,其治疗效果良好,差异有统计学意义(P<0.05);观察组改善机体功能恢复的有效率93.9%明显高于对照组患者78.8%,差异有统计学意义(P<0.05);观察组患者的临床治疗有效率89.4%明显高于对照组患者66.7%,差异有统计学意义(P<0.05)。结论伏立康唑联合康艾注射液治疗肺癌患者肺部真菌感染的效果显著,能改善患者的机体功能,减少患者住院时间,且预后较好,值得临床广泛推广应用。
OBJECTIVE To analyze the effect of voriconazole combined with Kang′ai injection in the treatment of pulmonary fungal infections in patients with cancer so as to provide references for effective treatment of pulmonary fungal infections .METHODS Totally 132 cases of lung cancer patients admitted in our hospital from Jun .2013 to Mar .2015 that were found to have pulmonary fungal infections were chosen as study objects .They were divided into observation group and control group with 66 cases each according to order of hospitalization and different treatments .The observation group received voriconazole combined with Kang′ai injection and the control group only received voriconazole .The indicators of the two groups were compared and analyzed .RESULTS The time of temperature recovery ,leukocyte recovery and hospitalization of the observation group were significantly shorter than those of the control group（P〈0 .05） .The recovery efficiency of improvement in body function of the obser‐vation group （93 .93% ） was significantly higher than the control group （78 .78% ） （P〈0 .05） .Clinical efficacy in patients in the observation group （89 .39% ） was significantly higher in patients in the control group （66 .66% ）（P〈0 .05） .CONCLUSION Voriconazole combined with Kang′ai injection proved to be effective in treating pulmonary fungal infections in patients with lung cancer for it can significantly improve the patient＇s body functions ,reduce hospitalization time ,and have good prognosis ,hence is worthy to be widely used .
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2015年第20期4670-4672,共3页
Chinese Journal of Nosocomiology
基金
浙江省卫生厅计划基金资助项目(20132333069)
关键词
肺癌
真菌感染
伏立康唑
康艾注射液
Lung cancer
Fungal infections
Voriconazole
Kang＇ai injection
