摘要
目的应用前节光学相干断层扫描(anterior segment optical coherence tomography,AS-OCT)对比研究白内障手术角膜微切口闭合性。方法年龄相关性白内障患者71例(71只眼)随机分为3.2mm组和2.2mm组,所有患者均在术后1d、1周、2周、1个月通过AS-OCT测量切口处角膜厚度、切口隧道裂隙面积及观察后弹力层脱离发生和恢复情况。结果1切口处角膜厚度:术后1周3.2mm切口处角膜厚度(822.40±77.10)μm低于2.2mm切口(862.53±68.01)μm(P=0.023)。2角膜隧道裂隙面积:术后2周3.2mm切口的内皮裂隙面积3507.50(13 900.00)μm2大于2.2mm切口0.00(4 154.00)μm2(P=0.010)。3角膜内皮裂隙发生及愈合情况:术后2周3.2mm切口组内皮裂隙发生率(57.1%)高于2.2mm切口组(33.3%),差异有统计学意义(P=0.044)。4角膜后弹力层脱离及愈合情况:术后1天3.2mm切口组有12例发生了后弹力层脱离、2.2mm切口组有13例;术后1个月3.2 mm切口组愈合11例(91.7%)、2.2 mm切口组愈合7例(53.8%),差异有统计学意义(P=0.035)。结论 AS-OCT对比研究表明,2.2mm切口较3.2mm标准切口相对来说愈合得快,但2.2mm切口对后弹力层的损伤较大。
Objective Comparative study of the closing of corneal micro-incision in cataract surgery with anterior segment optical coherence tomography （AS-OCT）. Methods Phacomulfication was performed with 3.2 mm or 2.2 mm incision for 71 patients（71 eyes）.The corneal thickness,the slit area of corneal tunnel and the corneal descemet membrane detachment were measured by AS-OCT in all the eyes 1 day,1 week,2 weeks and I month after surgery. Results ①The corneal thickness in the incision of the 3.2 mm group （822.40±77.10） μm was thinner than that of the 2.2 mm group（862.53±68.01） μm 1 week after the surgery （P =0.023）. ②As for the slit area of corneal tunnel,3.2 mm group was bigger than 2. 2 mm group after 2 weeks of surgery（P=0.010）.③The corneal endothelial gape： the rate of the 3.2 mm group （57.1%） was higher than that of the 2.2 mm group （33.3%） （P=0.044）.④As for the corneal descemet membrane detachment, there were 12 cases in 3.2 mm group 1 day after surgery,and 13 cases in 2.2 mm group.Eleven eases（91.7 %） in 3.2 mm group healed,comparing 7 cases（53.8 %） in 2. 2 mm group 1 month after surgery（P=0.035）.Conclusion The 2.2 mm incision heals faster than the 3. 2 mm, but the damage of 2.2 mm incision to the corneal descemet membrane isgreater.
出处
《河北医科大学学报》
CAS
2015年第9期1033-1037,共5页
Journal of Hebei Medical University
