摘要
目的 探讨布地奈德雾化吸入联合阿奇霉素治疗儿童支原体肺炎的临床效果。方法 选取2013年2月~2015年2月我院收治120例支原体肺炎患儿,将其随机分为观察组和对照组,对照组采用阿奇霉素治疗,观察组在对照组治疗基础上加用布地奈德雾化吸入治疗,比较两组患儿治疗效果及对血清IgE、IL-3、IL-4水平的影响。结果 观察组治疗总有效率为98.33%,明显高于对照组的83.33%,两组比较差异有统计学意义(P〈0.05);治疗后观察组患儿血清IgE、IL-3、IL-4水平均低于对照组,两组间各值比较差异有统计学意义(P〈0.05)。结论 布地奈德雾化吸入佐治儿童支原体肺炎可降低血清IgE、IL-3、IL-4水平,提高治疗效果,值得临床推广应用。
Objective To explore the influence of budesonide aerosol inhalation treating Mycoplasma pneumonia in children on serum IgE,IL-3 and IL-4 level. Methods 120 children with Mycoplasrna pneumonia treated in our hospital from February 2013 to February 2015 were selected and divided into two groups randomly,the observation group and the control group.The control group was treated with azithromycin,based on which the control group was treated with budesonide aerosol inhalation.The treatment effect between two groups and the influence on serum IgE,IL-3 and IL-4 level was compared respectively. Results The total effective rate of observation group was 98.33%,and that of control group was 83.33%,with statistical difference (P〈0.05).After treatment,the serum IgE,IL-3 and IL-4 level of the obser- vation group was lower than that of control group respectively,with statistical difference (P〈0.05). Conclusion Budesonide aerosol inhalation treating Mycoplasrnct pneumonia in children can reduce serum IgE,IL-3 and IL-4 level,and improve the treatment effect,which is worthy of clinical promotion and application.
出处
《中国当代医药》
2015年第27期85-87,共3页
China Modern Medicine
关键词
布地奈德
支原体肺炎
儿童
Budesonide
Mycoplasma pneumonia
Children