摘要
梗阻性黄疸是临床上常见的病理状态,梗阻性黄疸患者术后高并发症发生率及死亡率一直是术后恢复过程中一大难题。目前,肠源性内毒素血症被认为是梗阻性黄疸预后不良的主要原因,而梗阻性黄疸时,致病菌大量繁殖,肠道菌群失调,内毒素移位是肠源性内毒素血症发生的主要机制。因此如何有效地控制梗阻性黄疸时的肠道菌群失调成为现今研究的热点。本文就梗阻性黄疸时肠道菌群的变化,如何进行干预,降低患者术后并发症的发生率及死亡率的最新进展进行综述,希望对梗阻性黄疸的治疗提供新的思路及对策。
Obstructive jaundice is a common clinical pathology. High incidence of complications and mortality postoperatively of patients with obstructive jaundice have always been a big problem in the recovery process. At present, the intestinal endotoxemia is considered to be the main cause of poor prognosis of obstructive jaundice, and a large number of breeding bacteria, intestinal flora imbalance, endotoxin translocation are the main mechanism of happening of intestinal endotoxemia. Therefore, how to effectively control the intestinal dysbacteriosis caused by obstructive jaundice is becoming a hot spot of current research. This paper studied how to intervene the change of intestinal flora caused by obstructive jaundice for reducing the incidence of postoperative complications and mortality rate, to hope that new train of thought and countermeasures could be developed for the treatment of obstructive jaundice.
出处
《中华临床医师杂志（电子版）》
CAS
2015年第15期114-119,共6页
Chinese Journal of Clinicians(Electronic Edition)
关键词
黄疸
阻塞性
肠道菌群失调
微生态制剂
粪菌移植
Jaundice,obstructive
Intestinal dysbacteriosis
Probiotics
Fecal microbiota transplantation
