摘要
目的探究对轮状病毒肠炎患儿行喜炎平+利巴韦林联合治疗的临床效果。方法选取2012年4月至2015年4月接收的轮状病毒肠炎患儿74例为本次研究对象,按照分层法将其划分为对照组、实验组,分别行单纯性利巴韦林治疗、喜炎平+利巴韦林联合治疗,对比两组疗效。结果实验组行喜炎平+利巴韦林联合治疗后有效率(97.30%vs 75.68%)较对照组高,住院时间(5.81±1.33)d vs(9.23±1.86)d、退热时间(1.57±0.50)d vs(3.66±0.91)d、腹痛/腹泻缓解时间(2.77±0.44)d vs(3.78±0.44)d、恶心呕吐缓解时间(1.51±0.25)d vs(2.31±0.37)d、腹鸣缓解时间(4.11±0.55)d vs(6.43±0.82)d均较对照组短,差异有显著性(P<0.05)。结论对轮状病毒肠炎患儿行喜炎平+利巴韦林联合治疗,能有效改善患者消化道症状,促使体温下降,维护其神经功能,值得临床积极借鉴。
Objective To explore the clinical effect of Xiyanping and ribavirin in treating children with rotavirus enteritis. Methods Totally 74 children with rotavirus enteritis admitted into the hospital from April 2012 to April 2015 were selected as the research objects and were divided into the control group and the experimental group according to the hierarchical method. The two groups were respectively treated with simplex ribavirin and Xiyanping combined with ribavirin.The curative effects of the two groups were compared. Results The efficiency of the experimental group after the treatment of Xiyanping combined with ribavirin was（ 97. 30% vs 75. 68%） which was higher than that of the control group and the time of hospitalization（ d： 5. 81 ± 1. 33 vs 9. 23 ± 1. 86）,time of anti- febrile（ d： 1. 57 ± 0. 50 vs 3. 66 ±0. 91）,time of abdominal / diarrhea pain relief（ d： 2. 77 ± 0. 44 vs 3. 78 ± 0. 44）,time of nausea and vomiting relief（ d： 1. 51 ± 0. 25 vs 2. 31 ± 0. 37） and the remission time of borborygmus（ d： 4. 11 ± 0. 55 vs 6. 43 ± 0. 82） was shorter than that of the control group. The difference was significant（ P 〈0. 05）. Conclusions To treat children having rotavirus enteritis with Xiyanping and ribavirin can effectively alleviate the symptoms of digestive tract in patients,promte the drop of body temperature and maintain the nerve function,worthy of actively clinical reference.
出处
《医药论坛杂志》
2015年第9期45-47,共3页
Journal of Medical Forum
