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奥美拉唑联合莫沙必利治疗反流性食管炎的疗效观察 被引量:8

Efficacy of Omeprazole and Mosapride in treatment of reflux esophagitis
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摘要 目的分析对反流性食管炎患者行莫沙比利+奥美拉唑治疗的效果。方法择取2012年3月至2014年12月本院收治的反流性食管炎患者120例为研究对象,随机分成两组,对照组60例,临床中给予莫沙比利单一用药治疗,观察组60例,采用莫沙比利+奥美拉唑治疗。结果观察组患者的治疗有效率(96.7%)高于对照组(85.0%),两组比较差异具有统计学意义(P<0.05);观察组患者治疗后的生活质量总体健康评分为(38.44±8.67),对照组为(25.56±7.46),观察组高于对照组(P<0.05)。结论采用莫沙比利和奥美拉唑联合治疗反流性食管炎效果明显,安全性高,可显著提高临床疗效和生活质量,值得临床推广应用。 Objective To analyze the effect of reflux esophagitis patients with inflammatory Mosapride and Omeprazole treatment. Methods Choose to take from March 2012 to December 2014 in our hospital patients with reflux esophagitis 120 cases for the study were randomly divided into two groups,a control group of 60 patients,the clinic give Mosapride single drug treatment,observation group 60 cases,the use of Mosapride omeprazole. Results The effective treatment of patients( 96. 7%) was higher( 85. 0%),the difference was statistically significant( P〈 0. 05); The quality of life of patients in the observation group after treatment for overall health score( 38. 44 ± 8. 67),the control group( 25. 56 ± 7. 46),the observation group was higher( P〈 0. 05). Conclusion Mosapride and omeprazole combined treatment of reflux esophagitis effect is obvious,safe,can significantly improve the clinical efficacy and quality of life,worthy of clinical application.
出处 《医药论坛杂志》 2015年第9期34-35,共2页 Journal of Medical Forum
关键词 奥美拉唑 莫沙必利 反流性食管炎 生活质量 Omeprazole Mosapride Reflux esophagitis Quality of life
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