摘要
目的探讨早期胃癌行内镜黏膜下剥离术的有效性及可行性。方法将182例早期胃癌患者随机分为实验组及对照组,每组91例。实验组行内镜黏膜下剥离术,对照组行常规开腹根治性切除术,比较2组患者手术用时、住院时间、术中出血量、术后疼痛评分以及术后并发症发生率、手术切除效果,随访1年内分化与否及不同浸润深度患者复发情况。结果实验组手术用时、术后住院时间均短于对照组(P均<0.05),术中出血量少于对照组(P<0.05),术后疼痛评分及术后并发症发生率均明显低于对照组(P均<0.05);内镜黏膜下剥离手术完整切除率为92%,治愈性切除率为90%;2组中浸润深度重及未分化型患者术后复发率高(P均<0.05)。结论内镜黏膜下剥离术具有手术用时短、病灶完整切除率及治愈性切除率高、对患者伤害小、术后并发症发生率低、恢复快等优点,可避免过分治疗问题,值得临床推广应用。
Objective It is to investigate the effectiveness and feasibility influence of endoscopic submucosal dissection （ESD） for early gastric cancer. Methods 182 cases of patients with early gastric cancer were randomly divided into experi- mental group and control group, 91 cases in each group. The patients were treated with ESD in experimental group and with conventional open surgery in the control group, the difference between the two groups in the therapeutic effect, and the opera- tion time, hospitalization time, intraoperative blood loss, postoperative pain score, postoperative complications and removal effect were compared, the recurrence rate of the two groups were observed. Results In the experimental group, the operation time and hospitalization time were significantly short than those in control group （ all P 〈 0.05 ）, the bleeding volume was less than control group （ P 〈 0.05 ） , postoperative pain score and postoperative complications were significantly lower than the con- trol group （ all P 〈 0.05 ）. The ESD complete resection rate was 92% , curative resection rate was 90%. The recurrence rate in patients of deeper depth of invasion and undifferentiated type was higher （ all P 〈 0.05 ）. Conclusion ESD has a shorter op- eration time, the complete resection rate of lesions and curative resection rate, with small injury to patients, low rate of com- plications, faster recovery, it can avoid excessive treatment of the problem, worthy of clinical application.
出处
《现代中西医结合杂志》
CAS
2015年第27期2986-2988,共3页
Modern Journal of Integrated Traditional Chinese and Western Medicine
关键词
早期胃癌
内镜黏膜下剥离术
病灶完整切除率
治愈性切除率
early gastric cancer
endoscopic submucosal dissection
complete resection rate
curative resection rate
