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腰围身高比预测代谢综合征的切点研究 被引量:1

Optimal cut-off point of waist-to.height ratio for predicting metabolic syndrome
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摘要 目的研究腰围身高比与代谢综合征的关系,寻找腰围身高比预测代谢综合征的最佳切点。方法采用横断面调查方法,纳入2012年1月至2014年6月在福建医科大学附属泉州第一医院进行体检的343名人员,体检项目包括腰围、身高、体质量、血压、实验室检查(包括空腹血糖、口服葡萄糖耐量试验2h血糖、三酰甘油、高密度脂蛋白胆固醇)、CT测定腹腔内脂肪面积。通过受试者工作特征(ROC)曲线分析得到腰围身高比预测代谢综合征的最佳切点。结果343名体检者中共检出195例代谢综合征患者,总患病率为56.8%,其中男性患病率为70.2%(127/181),女性患病率为42.0%(68/162)。在ROC曲线分析中,男性腰围身高比预测代谢综合征的曲线下面积为0.664,女性为0.673,男性及女性腰围身高比预测代谢综合征的最佳切点值分别为0.5430(敏感度为88.2%,特异度为44.4%)和0.5683(敏感度为86.8%,特异度为46.8%)。结论泉州地区人群腰围身高比预测代谢综合征的最佳切点值男性为0.5430,女性为0.5683。 Objective To investigate the relationship between waist-to-height ratio and metabolic syndrome, in order to identify the optimal cut-off point of waist-to-height ratio for predicting metabolic syndrome. Methods In this cross-sectional study, we recruited 343 people who received physical examination in First Hospital of Quanzhou between January 2012 and June 2014, and collected the information of their waist circumference, height, weight, blood pressure, laboratory test results ( including fasting blood glucose, 2-hour glucose after oral glucose tolerance test, triglyceride, high-density lipoprotein cholesterol) and visceral fat area assessed by computed tomography. Then a receiver operating characteristic (ROC) curve analysis was used to estimate the optimal cut-off points of waist-to-height ratio for the prediction of metabolic syndrome. Results Among the 343 people, there were 195 metabolic syndrome patients, the prevalence rate was 56. 8% , which was 70.2% in men (127/181) and 42. 0% in women (68/162). In ROC curve analysis, the area under the curve of waist-to-height ratio for the prediction of metabolic syndrome was 0. 664 for men, and 0. 673 for women. The optimal cut-off point of waist-to-height ratio for predicting metabolic syndrome was 0. 543 0 ( sensitivity 88. 2% , specificity 44. 4% ) for men, and 0. 568 3 ( sensitivity 86. 8%, specificity 46. 8% ). Conclusion The opti- mal cut-off point of waist-to-height ratio for predicting metabolic syndrome in Quanzhou population is 0. 543 0 for men and 0. 568 3 for women.
出处 《中华临床营养杂志》 CAS CSCD 2015年第4期229-233,共5页 Chinese Journal of Clinical Nutrition
关键词 腰围身高比 代谢综合征 切点 Waist-to-height ratio Metabolic syndrome Cut-off point
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