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超声评价慢性血栓栓塞性肺动脉高压患者肺动脉压力与右心室功能的关系 被引量：18

Correlation between pulmonary arterial presure and right ventricular function by echocardiography in chronic thromboembolic pulmonary hypertension
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摘要 目的探讨经胸超声心动图评价慢性血栓栓塞性肺动脉高压（CTEPH）患者肺动脉压力与右心功能的相关性以及不同程度肺动脉压力下右室功能改变情况。方法CTEPH患者137例，以肺动脉收缩压（PASP）升高程度分为4组，组Ⅰ，50mmHg≤PASP〈70mmHg，20例；组Ⅱ，70mmHg≤PASP〈90mmHg，35例；组Ⅲ，90mmHg≤PASP〈110mmHg，55例；组Ⅳ，≥110mmHg，27例。超声心动图测量参数包括：PASP、三尖瓣反流面积（ATR）、左室横径（LVTD）、右室横径（RVTD）、肺动脉主干内径（DMPA）、左肺动脉内径（DLPA）及右肺动脉内径（DRPA）；右室功能参数包括：三尖瓣环收缩期峰值速度（s＇）、三尖瓣环收缩期位移（TAPsE）、右室心肌做功指数（RIMP）及右室面积变化分数（FAC）。结果肺动脉压力升高程度不同，CTEPH患者RVTD、TAPSE、FAC及RlMP差异均有统计学意义（均P〈0．05）。CTEPH患者右室结构、功能与PASP显著相关，并且随着肺动脉压力的升高，右室扩大显著，右室功能受损。结论超声心动图有助于评估CTEPH患者右心功能改变情况，为临床治疗及预后评估提供依据。 Objective To discuss the correlation between right ventricular function and systolic pulmonary artery pressure （PASP） in patients with chronic thromboembolic pulmonary hypertension （CTEPH） and explore the change of right ventricular function under different degree of PASP. Methods One hundred and thirty-seven CTEPH patients were divided into four groups by PASP.. Group Ⅰ （50 mmHg≤PASP〈70 mmHg） ,20 cases;Group Ⅱ （70 mmHg≤PASP〈90 mmHg） ,35 cases;Group Ⅲ ,55 cases （90 mmHg≤PASP〈110 mmHg） ; Group Ⅳ（PASP〈 110 mmHg）, 27 cases. Echocardiographic parameters include ： PASP, tricuspid regurgitation area （Axe）, left ventricular transverse diameter （LVTD）, right ventricular transverse diameter （RVTD）, inner diameter of main pulmonary artery （DMpA）, inner diameter of left arterial branch （DLpA）, inner diameter of right pulmonary arterial branch （DRvA）. Right ventricular function parameters include~ tissue Doppler-derived tricuspid lateral annular systolic velocity （s＇）, tricuspid annular plane systolic excursion （TAPSE）, RV index of myocardial performance （RIMP） and right ventricular fractional area change （FAC）. Results There were significant differences in RVTD, TAPSE, FAC and RIMP in CTEPH patients under different PASP（ P 〈0.05）. RV structure and function was significantly correlated with PASP in CTEPH patients. With the elevation of PASP, RV was significantly enlarged and RV function becomes worse. Conclusions Echoeardiography may contribute to evaluate RV function in CTEPH patients and provide basis for clinical treatment and prognosis evaluation.
作者 王怡丹 李一丹 吕秀章 吴雅峰 王丽 朱维维
机构地区 首都医科大学附属北京朝阳医院心脏超声科
出处 《中华超声影像学杂志》 CSCD 北大核心 2015年第8期648-651,共4页 Chinese Journal of Ultrasonography
基金 国家自然科学基金项目（81401420） 北京市“215”高层次卫生技术人才学科骨干项目（2014-3-027） 首都临床特色应用研究项目（Z141107002514074） 首都卫生发展科研专项项目（2014-2-1061）
关键词 超声心动描记术 肺栓塞 高血压 肺性 心室功能 右 Echocardiography Pulmonary embolism Hypertension, pulmonary Ventricular function, right
分类号 R540.45 [医药卫生—心血管疾病] R544.1 [医药卫生—心血管疾病]
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参考文献15

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共引文献6

同被引文献162

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引证文献18

二级引证文献107

中华超声影像学杂志
2015年 第8期

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