摘要
目的研究不同水平糖化血红蛋白对糖尿病合并脑梗死的影响。方法将糖尿病合并脑梗死患者200例根据糖化血红蛋白水平分为4组：A组（Hb A1C=6%∽7%）49例、B组（Hb A1C=7%∽8%）51例、C组（Hb A1C=8%∽9%）48例和D组（Hb A1C〉9%）52例。观察患者颈动脉粥样斑块情况、6个月内再发脑梗死及神经功能恢复情况。结果 A、B、C和D组再发脑梗死率分别是0、0、14.29%和23.08%,A组、B组最低。颈动脉斑块厚度A最低,D组最高,各组间差异均有统计学意义（P〈0.05）。随着时间延长,四组患者的神经功能缺损评分均有下降。各相同时间点四组间比较,评分在A组最低,其次是B组、C组,最后为D组。结论糖化血红蛋白与糖尿病合并脑梗死病情发展有密切关系,可根据其预测病情发展并指导治疗。
Objective To study the effects of different levels of glycosylated hemoglobin （HbA1C） on diabetes complicated with cerebral infarction. Methods 200 patients were divided into 4 groups according to the level of HbA1C, group A（HbA1C=6% to 7%, 49 cases）, group B（HbA1C=7% to 8%,51 cases）, group C（HbA1C=8% to 9%,48 cases） and group D（HbA1C〉9%, 52 cases）. The carotid atherosclerotic plaques, recurrent rate of cerebral infarction and recovery of neurological function in 6 months were observed.Results The recurrent rate of cerebral infarction was 0, 0, 14.29%, and 23.08% in group A, B, C and D, the group A and group B was the lowest. The thickness of carotid artery plaque was the lowest in group A and the highest in group D, the differences between groups were statistically significant（P〈0.05）. With the time prolonged, the scores of neural function defect of four groups were decreased. Scores were the lowest in group A, followed by the group B, group C, finally as group D.Conclusion There are close relationship between HbA1C and diabetic complicated with cerebral infarction. We can predict disease development and guide the treatment according to it.
出处
《中国医药科学》
2015年第11期202-204,共3页
China Medicine And Pharmacy
关键词
糖化血红蛋白
糖尿病
脑梗死
Glycosylated hemoglobin
Diabetes
Cerebral infarction
