摘要
[目的]为评价恩诺沙星合成抗原免疫对动物机体的影响提供参考。[方法]用恩诺沙星合成抗原免疫小鼠,探讨恩诺沙星合成抗原免疫对小鼠肝脏组织中谷草转氨酶(AST)和谷丙转氨酶(ALT)活性的影响。[结果]对照组小鼠AST活性为(384.34±74.06)U/mg prot,试验组为(358.04±48.63)U/mg prot,差异不显著(P>0.05)。对照组小鼠ALT活性为(934.92±117.94)U/mg prot,试验组为(523.78±94.60)U/mg prot,差异极显著(P<0.01)。[结论]恩诺沙星合成抗原免疫对小鼠肝脏组织ALT活性有抑制作用,但对AST活性没有明显影响。
[ Objective ] The research aimed to provide references for evaluating the effects of enrofloxacin synthetic antigen on the transaminase activity in the liver of mice. [ Method] The mice was immunized with enrofloxacin synthetic antigen to discuss its effects on the activities of AST and ALT in the liver of mice. [ Result] The activity of AST of mice in the control group was （384.34 ±74.06） U/mg prot and that in test group was （358.04 ±48.63 ） U/mg prot, there was no significant difference between control group and test group（ P 〉 0. 05 ）. The activity of ALT of mice in the control group was （934.92 ±117.94） U/mg prot and that in test group was（523.78 ±94.60） U/mg prot, there was extremely significant difference （P 〈 0.01 ）. [ Conclusion ] The immunization with enrofloxacin synthetic antigen could inhibit the activity of ALT in the liver of mice, but it had no obvious effect on the activity of AST.
出处
《安徽农业科学》
CAS
2015年第25期124-125,128,共3页
Journal of Anhui Agricultural Sciences
基金
安徽省蚌埠市科技局项目(ZRC2011597)
关键词
恩诺沙星合成抗原
谷丙转氨酶
谷草转氨酶
肝脏
Enrofloxacin synthetic antigen
Alanine aminotransferase （ALT）
Aspartate transaminase （AST）
Liver
