摘要
采用层层组装技术,在色谱硅胶表面交替沉积带相反电荷的聚烯丙基胺盐酸盐(PAH)和聚乙烯-alt-马来酸十醇酯(PEMADEC),制备一种新型聚电解质多层膜(PAH/PEMADEC)6包覆的硅胶色谱固定相,利用红外光谱和元素分析表征多层膜结构。以6种苯的衍生物和9种苯胺类化合物为分析物,评价PAH/PEMADEC多层膜固定相的色谱性质。结果显示多层膜固定相与分析物间同时存在疏水和亲水相互作用,为制备混合模式固定相提供了一种新途径。
A novel high performance liquid chromatograph （ HPLC） stationary phase was fabricated via layer-by-layer （ LBL ） self-assembly of poly （ allylamine hydrochloride ） （ PAH ） and poly （ decyl ethylene-alt-maleate ） （ PEMADEC ） on the surface of the silica.The composition of （ PAH/PEMADEC ） 6 multilayer were characterized with infrared spectrometry and elemental analyzer.6 alkylbenzenes and 9 substituted anilines were selected as analytes to evaluate the chromatographic property of （ PAH/PEMADEC） 6 multilayer stationary phase.The results indicated that both hydrophobic hydrophilic interactions existed between the stationary phase and analytes.This provided a new strategy for the preparation of HPLC stationary with both reversed-phase and hydrophilic interaction liquid chromatographic modes.
出处
《广州化工》
CAS
2015年第15期128-130,共3页
GuangZhou Chemical Industry
基金
郑州科技人才队伍建设计划-科技创新团队(131PCXTD605)
关键词
逐层自组装
聚电解质多层膜
固定相
layer-by-layer self-assembly
polyelectrolyte multilayer
stationary phase
