摘要
急性髓系白血病(AML)为1类遗传学高度异质性的血液系统恶性疾病,无论是疾病复发/难治(R/R),治疗效果往往较差。目前仍缺乏有效的治疗策略,随着对AML发病机制的深入研究,新型化疗药物及化疗组合方案层出不穷。2014年第56届美国血液学会(AsH)年会报道的关于R/RAML的临床研究,无疑为攻克此类疾病带来新希望。笔者拟就R/RAML临床治疗的研究进展进行综述。
Acute myeloid leukemia (AML) is a kind of heterogeneous disease. Whether the disease is relapse/refractory (R/R) or not, therapeutic effects are often poor. Now, it is still lack of effective therapy to solve this problem. With the in-depth study of the pathogenesis of AML, new chemotherapy drugs and chemotherapy combination emerge in an unending flow. The 56th American Society of Hematology (ASH) shares results of R/R AML clinical studies, which opening up new prospects for R/R AML treatment.
出处
《国际输血及血液学杂志》
CAS
2015年第4期335-339,共5页
International Journal of Blood Transfusion and Hematology
基金
基金项目:国家自然科学基金资助项目(81360641)
关键词
白血病
髓样
急性
复发
临床试验
Leukemia, myeloid, acute, Recurrence
Clinical trial